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前交叉韧带重建术前进行半月板修复时失败率较高:对伴有前交叉韧带损伤和创伤性半月板撕裂的两阶段手术的分析。

High failure rate in meniscal repair when preceding anterior cruciate ligament reconstruction: An analysis of two-stage surgery for concomitant ACL injury and traumatic meniscus tear.

作者信息

López Personat Adolfo, Cristiani Riccardo, Stålman Anders, Wänman Johan, Von Essen Christoffer

机构信息

Department of Orthopedics, Örebro University Hospital, Örebro, Sweden.

Capio Artro Clinic, FIFA Medical Centre of Excellence, Sophiahemmet Hospital, Stockholm, Sweden.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2025 Jul;33(7):2323-2333. doi: 10.1002/ksa.12593. Epub 2025 Jan 29.

Abstract

PURPOSE

To investigate the failure rate, predictive factors associated with failure and clinical outcomes after a two-stage surgery; meniscus repair followed by subsequent anterior cruciate ligament (ACL) reconstruction (ACLR).

METHODS

Patients with a concomitant traumatic meniscus tear and ACL injury who underwent a two-stage surgery between January 2015 and January 2021 were identified. The primary outcome was meniscal repair failure, defined as a reoperation (re-repair or resection). A Cox-regression analysis was used in order to analyse factors associated with meniscal repair failure within 3 years after the primary surgery for a meniscal repair. Secondary outcomes were range of motion (ROM), anterior knee laxity and the Knee Injury and Osteoarthritis Outcome Score (KOOS) at 1- and 2-year follow-up. The thresholds of patient acceptable symptom state (PASS), treatment failure (TF) and minimum important change (MIC) were applied to KOOS4 (mean score of the KOOS Pain, Symptoms, Sports/Rec and QoL subscales).

RESULTS

A total of 150 patients were included. The meniscal repair failure rate after 3 years was 36.7%. Failure of meniscal repair was significantly associated with a time interval >1 year between the meniscal repair to the ACLR (hazard ratio [HR] = 2.5; 95% confidence interval [CI] = 1.2-5.5; p < 0.01), medial meniscus repair (HR = 2.3; 95% CI = 1.6-3.4; P < 0.01), and female sex (HR = 1.42; 95% CI = 1.0-1.9; p = 0.01). The age of the patient was not associated with meniscal repair failure. At the 6-month follow-up, most patients (72.5%) showed less than 2 mm of knee laxity; four patients (6.7%) experienced loss of extension and four patients (1.7%) experienced loss of flexion. On the KOOS4, at the 2-year follow-up, PASS was achieved in 53.4%, TF occurred in 1.7%, and MIC was reached in 36.4% of patients.

CONCLUSION

The meniscus repair failure rate after the staged procedure was 36.7% at 3 years. A longer time interval from meniscal repair to ACLR, medial meniscus repair, and female sex were associated with an increased risk of meniscal repair failure. Age was not associated with meniscal repair failure.

LEVEL OF EVIDENCE

Level IV, case series retrospective study.

摘要

目的

探讨两阶段手术(半月板修复术后二期进行前交叉韧带重建术)后的失败率、与失败相关的预测因素及临床结局。

方法

纳入2015年1月至2021年1月期间接受两阶段手术的合并创伤性半月板撕裂和前交叉韧带损伤的患者。主要结局为半月板修复失败,定义为再次手术(再次修复或切除)。采用Cox回归分析来分析半月板初次修复术后3年内与半月板修复失败相关的因素。次要结局为随访1年和2年时的活动范围(ROM)、膝关节前向松弛度以及膝关节损伤和骨关节炎疗效评分(KOOS)。将患者可接受症状状态(PASS)、治疗失败(TF)和最小重要变化(MIC)的阈值应用于KOOS4(KOOS疼痛、症状、运动/娱乐和生活质量子量表的平均分)。

结果

共纳入150例患者。3年后半月板修复失败率为36.7%。半月板修复失败与半月板修复至前交叉韧带重建术的时间间隔>1年(风险比[HR]=2.5;95%置信区间[CI]=1.2 - 5.5;p<0.01)、内侧半月板修复(HR=2.3;95%CI=1.6 - 3.4;P<0.01)以及女性性别(HR=1.42;95%CI=1.0 - 1.9;p=0.01)显著相关。患者年龄与半月板修复失败无关。在6个月随访时,大多数患者(72.5%)膝关节松弛度小于2mm;4例患者(6.7%)出现伸直受限,4例患者(1.7%)出现屈曲受限。在KOOS4方面,随访2年时,53.4%的患者达到PASS,1.7%出现TF,36.4%达到MIC。

结论

分期手术后3年半月板修复失败率为36.7%。半月板修复至前交叉韧带重建术的时间间隔延长、内侧半月板修复以及女性性别与半月板修复失败风险增加相关。年龄与半月板修复失败无关。

证据水平

IV级,病例系列回顾性研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7cb/12205414/9c1df1bd2626/KSA-33-2323-g003.jpg

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