Dörner G, Thoelke H, Mohnike A, Schneider H
Exp Clin Endocrinol. 1985 Feb;85(1):1-6. doi: 10.1055/s-0029-1210414.
Men who were born in war and post-war periods with shortage of food supply (1943-47) showed a markedly low prevalence of insulin-treated diabetes mellitus (ITDM), but not of non-insulin-treated diabetes mellitus (NITDM) in later life. A significant increase (+54%) of ITDM prevalence was observed between 1976 and 1982 for subjects at 26-31 years of age, who were born in a post-war period (1945-50) with shortage and a peace period (1951-56) without shortage of food supply, respectively. By contrast, there was not found an increase--but even a slight decrease (-14%)--of ITDM prevalence between 1976 and 1982 for subjects at 38-43 years of age, who were born in a peace period (1933-38) without shortage and a war period (1939-44) with shortage of food supply, respectively. A similar clear dependence of diabetes prevalence on food supply in perinatal life could not be observed for NITDM. On the other hand, the prevalence of NITDM appeared to be significantly dependent--in contrast to ITDM--on food supply in adulthood.
出生于战争时期及战后食物供应短缺时期（1943 - 1947年）的男性，在晚年时接受胰岛素治疗的糖尿病（ITDM）患病率显著较低，但非胰岛素治疗的糖尿病（NITDM）患病率并非如此。在1976年至1982年期间，分别出生于战后食物供应短缺时期（1945 - 1950年）和食物供应充足的和平时期（1951 - 1956年）、年龄在26 - 31岁的受试者中，观察到ITDM患病率显著上升（+54%）。相比之下，在1976年至1982年期间，分别出生于食物供应充足的和平时期（1933 - 1938年）和食物供应短缺的战争时期（1939 - 1944年）、年龄在38 - 43岁的受试者中，未发现ITDM患病率上升，甚至略有下降（-14%）。对于NITDM，未观察到围产期食物供应与糖尿病患病率之间有类似的明显关联。另一方面，与ITDM不同，NITDM的患病率似乎显著依赖于成年期的食物供应。
