Dörner G, Mohnike A, Thoelke H
Exp Clin Endocrinol. 1984 Oct;84(2):129-33. doi: 10.1055/s-0029-1210377.
In order to investigate the possible influence of pre- and/or early postnatal nutrition on the development of diabetes mellitus in later life, diabetes prevalences were ascertained in subjects of similar ages who were born in different periods with or without shortage of food supply. Between 1974 and 1982 the total prevalence of diabetes mellitus increased in Berlin/GDR by 26%. A significantly higher increase of diabetes prevalence (approximately 90%) was found between 1974 and 1982 for subjects at 26-33 years of age, whose years of birth changed from a "hypocaloric war and post-war period (1941-1948)" to a "relatively hypercaloric peace period (1949-1956)". By contrast, there was not found any significant increase of diabetes prevalence between 1974 and 1982 for subjects at 34-41 years of age, whose years of birth changed from a "relatively hypercaloric period (1933-1940)" to a "hypocaloric period (1941-1948)". These findings give further evidence for the dependence of diabetes prevalence in later life on nutrition in perinatal life.
为了研究产前和(或)产后早期营养对晚年糖尿病发病可能产生的影响,我们确定了不同时期出生、有或没有食物供应短缺情况的相似年龄人群的糖尿病患病率。1974年至1982年间,柏林/民主德国的糖尿病总患病率上升了26%。在1974年至1982年间,对于年龄在26至33岁之间、出生年份从“热量不足的战争及战后时期(1941 - 1948年)”转变为“相对高热量的和平时期(1949 - 1956年)”的人群,发现糖尿病患病率显著上升(约90%)。相比之下,对于年龄在34至41岁之间、出生年份从“相对高热量时期(1933 - 1940年)”转变为“热量不足时期(1941 - 1948年)”的人群,在1974年至1982年间未发现糖尿病患病率有任何显著上升。这些发现进一步证明了晚年糖尿病患病率对围产期营养的依赖性。