Kaplan B J
Exp Neurol. 1985 May;88(2):425-36. doi: 10.1016/0014-4886(85)90204-3.
Electrocortical polyspiking has been reported in guinea pigs, tottering mice, and several strains of laboratory rats. Some investigators have interpreted the polyspiking activity (PSA) to be epileptic in nature, specifically analogous to human petit mal spike-wave discharges; others have assumed PSA to be the rodent equivalent of human mu and feline sensorimotor rhythms. This article provides additional data on PSA in rats, consistent with previous reports that it is associated with behavioral immobility, occurs spontaneously, is bilaterally symmetrical, has a frequency of about 7 to 9/s, and is associated with vibrissa tremor. The PSA frequency varied in relation to the difference between fast and slow vibrissa tremor, as reported previously. A review of these data and the nine earlier publications on PSA reveals that the epileptic nature of PSA is still unproven, and there is strong support for the proposal that it is a normal EEG pattern.
在豚鼠、蹒跚小鼠和几种实验室大鼠品系中已报道存在皮层多棘波发放。一些研究人员将多棘波发放活动（PSA）解释为本质上是癫痫性的，具体类似于人类小发作的棘慢波放电；另一些人则认为PSA相当于人类的μ节律和猫的感觉运动节律。本文提供了关于大鼠PSA的更多数据，与之前的报道一致，即它与行为不动有关，自发出现，双侧对称，频率约为7至9次/秒，且与触须震颤有关。如先前报道，PSA频率随快速和慢速触须震颤之间的差异而变化。对这些数据以及之前九篇关于PSA的出版物的综述表明，PSA的癫痫本质仍未得到证实，且有强有力的证据支持它是一种正常脑电图模式的提议。
