ATP诱发儿茶酚胺释放过程中分离出的嗜铬颗粒大小的变化。
Changes in the size of isolated chromaffin granules in ATP-evoked catecholamine release.
作者信息
Warashina A
出版信息
FEBS Lett. 1985 May 6;184(1):87-9. doi: 10.1016/0014-5793(85)80659-1.
PMID:3987907
Abstract
The average size of chromaffin granules isolated from bovine adrenal medullae was analyzed by a quasi-elastic laser light scattering method. The granule diameter increased by a factor of 1.3 by addition of Mg-ATP in the medium. The ATP effect was completely suppressed in the presence of an anion transport blocker (SITS), and partly depressed by a proton transport blocker (DCCD).
摘要
采用准弹性激光散射法分析了从牛肾上腺髓质分离出的嗜铬颗粒的平均大小。通过在培养基中添加Mg-ATP，颗粒直径增加了1.3倍。在存在阴离子转运阻滞剂（SITS）的情况下，ATP的作用被完全抑制，而在存在质子转运阻滞剂（DCCD）的情况下，ATP的作用部分受到抑制。
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