Poudel Ranjita, Dougan Skye O, Yates Helen, Sawyer Leslie, Martinez Ursula, Brandon Karen O, Sutton Steven K, Vidrine Damon J, Ritterband Lee M, Wiseman Kara P, Vickerman Katrina A, Turner Kea, Byrne Margaret M, Yang Min-Jeong, Horta Marilyn, Brandon Thomas H, Vinci Christine
Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Department of Psychology, University of South Florida, Tampa, FL, USA.
Contemp Clin Trials. 2025 Mar;150:107827. doi: 10.1016/j.cct.2025.107827. Epub 2025 Jan 27.
Augmented Reality (AR) is a rapidly developing technology with potential utility for treating addictive behaviors, including tobacco smoking. AR inserts digital images into a natural real-time scene as viewed on a smartphone or other video devices. With respect to smoking cessation, AR can place virtual smoking cues (i.e., smoking "triggers") within an individual's natural smoking environment. Repeated exposure to these cues could enhance smoking cessation through Pavlovian extinction processes.
In a usability study (N = 10), we evaluated the acceptability of a smoking cessation AR app to inform modifications to the app prior to an upcoming randomized controlled trial (RCT). For the subsequent RCT, individuals who enroll in a state tobacco quitline will be referred to the study and, if eligible and consented, randomized to use the app with AR features or without AR features (control) for 5 weeks. The efficacy of the AR features to enhance smoking cessation in the context of concurrent quitline treatment will be evaluated with the primary outcome of self-reported 7-day point-prevalence cigarette abstinence at 6 months post-enrollment. Implementation will be evaluated via incremental cost-effectiveness analyses and interviews with participants, quitline staff, and app coaches.
Interventions utilizing emerging mobile technologies such as AR have the potential, compared to traditional therapies, to improve both reach and efficacy by administering therapeutic elements in users' natural environments. Our AR app will target tobacco smoking, but the approach could be used to deliver exposure therapies for other addictive behaviors, as well as anxiety disorders.
NCT06088498.
增强现实(AR)是一项快速发展的技术,在治疗成瘾行为(包括吸烟)方面具有潜在效用。AR可将数字图像插入智能手机或其他视频设备上所看到的自然实时场景中。关于戒烟,AR可在个人自然吸烟环境中放置虚拟吸烟提示(即吸烟“触发因素”)。反复接触这些提示可通过巴甫洛夫消退过程增强戒烟效果。
在一项可用性研究(N = 10)中,我们评估了一款戒烟AR应用程序的可接受性,以便在即将到来的随机对照试验(RCT)之前对该应用程序进行修改。对于后续的RCT,报名参加州戒烟热线的个人将被转介到该研究中,如果符合条件并同意,将被随机分配使用具有AR功能的应用程序或不具有AR功能的应用程序(对照组),为期5周。将以入组后6个月自我报告的7天点流行率戒烟情况作为主要结果,评估AR功能在同时进行热线治疗的背景下增强戒烟效果的功效。将通过增量成本效益分析以及对参与者、戒烟热线工作人员和应用程序指导人员的访谈来评估实施情况。
与传统疗法相比,利用AR等新兴移动技术的干预措施有可能通过在用户自然环境中实施治疗要素来提高覆盖面和疗效。我们的AR应用程序将以吸烟为目标,但该方法可用于为其他成瘾行为以及焦虑症提供暴露疗法。
NCT06088498。