Gibson L E, Perry H O
Geriatrics. 1985 May;40(5):87-9, 91-2.
Leukoplakia is a clinical term that may histologically represent actinic changes or frank squamous cell carcinoma. Because the nature of dysplasia may differ in various portions of the involved lip, adequate histologic examination is mandatory. Histologic characteristics of squamous cell carcinoma include loss of cell organization and orientation, loss of intercellular bridges, presence of nuclear atypia and mitotic figures, and premature cell keratinization.
白斑是一个临床术语，在组织学上可能表现为光化性改变或明显的鳞状细胞癌。由于发育异常的性质在受累唇部的不同部位可能有所不同，因此必须进行充分的组织学检查。鳞状细胞癌的组织学特征包括细胞排列和定向丧失、细胞间桥丧失、核异型性和有丝分裂象的存在以及细胞过早角化。
