Gopalakrishnan Karpaka Vinayakam, Prabhakaran Kawushik Kumar
Department of General Surgery, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India.
Sci Rep. 2025 Jan 29;15(1):3717. doi: 10.1038/s41598-025-87960-2.
Ganglion cysts are benign soft tissue tumors that commonly occur in the joints, especially the wrist. Surgical excision and steroid injection are the two main treatment options; however, their efficacy remains unclear. This prospective interventional control trial included 54 patients with ganglion cysts treated between March 2023 and March 2024 at Saveetha Medical College Hospital, Chennai. Patients were divided into two groups: Group A underwent surgical excision and Group B received aspiration followed by 40 mg of intralesional triamcinolone acetonide injection. The highest incidence was observed in younger patients aged 14-19 years (13 patients), with more females (57.4%) affected. The cysts were equally distributed between the left and right hands. All patients presented with swelling, and 59.3% experienced pain/discomfort. In Group A surgical excision success rate was 92.5%, with a 7.5% recurrence rate. Group B had a lower success rate (64.3%) and higher recurrence rate (35.7%) with aspiration and injection. Surgical excision demonstrated significantly better outcomes, with higher success and lower recurrence rates than aspiration and steroid injection for the management of ganglion cysts. Therefore, this should be considered the preferred treatment option.
腱鞘囊肿是常见于关节尤其是手腕部的良性软组织肿瘤。手术切除和类固醇注射是两种主要的治疗选择；然而，它们的疗效仍不明确。这项前瞻性干预对照试验纳入了2023年3月至2024年3月在金奈萨维塔医学院医院接受治疗的54例腱鞘囊肿患者。患者被分为两组：A组接受手术切除，B组接受抽吸并在病灶内注射40毫克曲安奈德。发病率最高的是14 - 19岁的年轻患者（13例），女性受影响更多（57.4%）。囊肿在左右手之间分布均匀。所有患者均有肿胀表现，59.3%的患者有疼痛/不适症状。A组手术切除成功率为92.5%，复发率为7.5%。B组抽吸注射的成功率较低（64.3%），复发率较高（35.7%）。对于腱鞘囊肿的治疗，手术切除的效果明显更好，成功率更高，复发率低于抽吸和类固醇注射。因此，应将其视为首选的治疗方案。
