Sincar Kubra, Tas Muhammed Dara, Palamar Melis, Egrilmez Sait, Yagci Ayse, Barut Selver Ozlem
Department of Ophthalmology, Ege University Faculty of Medicine, 35100, Bornova, Izmir, Türkiye.
Ocular Surface Research Laboratory, Ege University, Faculty of Medicine, Izmir, Türkiye.
Int Ophthalmol. 2025 Jan 29;45(1):51. doi: 10.1007/s10792-025-03428-2.
The aim of the present study is to examine the demographic data and clinical features of ocular surface injuries due to thermal burns and to evaluate LSCD in the light of global consensus.
Thirty-three eyes of 20 cases with ocular surface injury due to thermal burn who attended to the clinic between 2012 and 2023 were included in the study. LSCD severity was staged according to the global consensus which was published in 2019.
The mean age of 20 cases was 45.8 ± 13.362 (19-78) and female/male ratio was 4/16. The causes of thermal burns were exposure to fire in 10 (50%), molten metal in 5 (25%), pressure cooker explosion in 3 (15%), and hot water in 2 (10%) cases. The number of cases who recovered without sequelae was 15. The observed sequelaes were LSCD (21.2%), symblepharon (6.06%), and corneal opacity (9.09%). Considering the distribution of LSCD, 28.57% of the eyes were Stage Ia, 14.28% were Stage Ib, 28.57% were Stage IIb, 28.57% were Stage III. The symblepharon was Stage IIa in 2 patients. Surgery was performed in 4 patients with sequelae (penetrating keratoplasty in 1, corneal debridement in 1, limbal autograft in 1, amniotic membrane transplantation + symblepharon excision + limbal autograft in 1 eyes).
Most of the thermal injuries heal without sequelae. If a sequela takes place, the most common one is severe LSCD-half of which are severe.
本研究旨在探讨热烧伤导致眼表损伤的人口统计学数据和临床特征，并根据全球共识评估角膜缘干细胞缺乏（LSCD）情况。
本研究纳入了2012年至2023年间到门诊就诊的20例因热烧伤导致眼表损伤的患者的33只眼睛。根据2019年发表的全球共识对LSCD严重程度进行分期。
20例患者的平均年龄为45.8±13.362岁（19 - 78岁），女性/男性比例为4/16。热烧伤的原因包括：10例（50%）因接触火焰，5例（25%）因接触熔融金属，3例（15%）因高压锅爆炸，2例（10%）因接触热水。无后遗症康复的病例有15例。观察到的后遗症包括角膜缘干细胞缺乏（21.2%）、睑球粘连（6.06%）和角膜混浊（9.09%）。考虑角膜缘干细胞缺乏的分布情况，28.57%的眼睛为Ia期，14.28%为Ib期，28.57%为IIb期，28.57%为III期。2例患者的睑球粘连为IIa期。4例有后遗症的患者接受了手术（1例行穿透性角膜移植术，1例行角膜清创术，1例行自体角膜缘移植术，1只眼行羊膜移植术 + 睑球粘连切除术 + 自体角膜缘移植术）。
大多数热烧伤可无后遗症愈合。如果出现后遗症，最常见的是严重的角膜缘干细胞缺乏，其中一半为重度。
