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哺乳动物耳蜗反应中微观结构的来源。

Sources of Microstructure in Mammalian Cochlear Responses.

作者信息

Dewey James B

机构信息

Caruso Department of Otolaryngology-Head & Neck Surgery, University of Southern California, Los Angeles, CA, USA.

出版信息

J Assoc Res Otolaryngol. 2025 Feb;26(1):1-15. doi: 10.1007/s10162-025-00974-5. Epub 2025 Jan 29.

Abstract

Quasiperiodic fluctuations with frequency are observed in a variety of responses that either originate from or strongly depend on the cochlea's active mechanics. These spectral microstructures are unique and stable features of individual ears and have been most thoroughly studied in behavioral hearing thresholds and otoacoustic emissions (OAEs). While the exact morphology of the microstructure patterns may differ across measurement types, the patterns are interrelated and are thought to depend on common mechanisms. This review summarizes the characteristics and proposed origins of the microstructures observed in behavioral and OAE responses, as well as other mechanical and electrophysiological responses of the mammalian cochlea. Throughout, the work of Glenis Long and colleagues is highlighted. Long contributed greatly to our understanding of microstructure and its perceptual consequences, as well as to the development of techniques for reducing the impact of microstructure on OAE-based assays of cochlear function.

摘要

在各种源于或强烈依赖于耳蜗主动力学的反应中,观察到了具有特定频率的准周期波动。这些频谱微结构是个体耳朵独特且稳定的特征,并且在行为听力阈值和耳声发射(OAE)方面得到了最为深入的研究。虽然微结构模式的确切形态可能因测量类型而异,但这些模式相互关联,并且被认为依赖于共同的机制。本综述总结了在行为和OAE反应中观察到的微结构的特征及其推测的起源,以及哺乳动物耳蜗的其他力学和电生理反应。在整个过程中,重点介绍了格莱尼斯·朗及其同事的工作。朗对我们理解微结构及其感知后果,以及对减少微结构对基于OAE的耳蜗功能检测影响的技术发展做出了巨大贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d11/11861815/5b22ef802eb3/10162_2025_974_Fig1_HTML.jpg

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