Huo Zhikui, Sun Yao, Chang Jinghui, Li Guo-Dong, Shi Jian, Quan Cheng, Zhang Li-Na, Yang Ting-Ting, Shang Feng-Jia, Yang Yong-Ping
The Department of General Surgery, The Second Hospital of Jilin University, Changchun, 130041, China.
World J Surg Oncol. 2025 Jan 29;23(1):31. doi: 10.1186/s12957-025-03676-7.
Extraskeletal osteosarcoma (ESOS) is a rare kind of sarcoma with a low preoperative diagnosis and a poor prognosis. ESOS arising from abdominal mesentery is extremely rare. Increasing diagnostic methods and standardizing treatment protocols are crucial issues of ESOS.
We report the case of a 52-year-old female ESOS patient. She had a history of ovarian carcinoma (stage IIIC) surgery two years before, with five cycles of chemotherapy. A mass was found during postoperative examinations. A R0 surgical resection was performed. Post-operational pathological report plus intra-surgery findings supported a diagnosis of ESOS. She is still alive 10 months post-operationally, with routine blood and radiographical examinations.
Enhancing awareness of this extremely rare disease together with advancements in diagnostic methods will hopefully enable earlier recognition and initiation of treatment. Protocols for standardizing treatments require a larger multi-center collaboration and more data analysis.
骨外骨肉瘤（ESOS）是一种罕见的肉瘤，术前诊断率低且预后较差。起源于腹部肠系膜的ESOS极为罕见。增加诊断方法和规范治疗方案是ESOS的关键问题。
我们报告一例52岁女性ESOS患者。她两年前有卵巢癌（IIIC期）手术史，并接受了五个周期的化疗。术后检查发现一个肿块。进行了R0手术切除。术后病理报告及术中发现支持ESOS的诊断。术后10个月她仍存活，进行了常规血液和影像学检查。
提高对这种极为罕见疾病的认识以及诊断方法的进步有望实现早期识别和治疗。规范治疗方案需要更大规模的多中心合作和更多的数据分析。
