Ito Shingo, Terado Yuichi, Shimojima Reiko, Hara Yoshiaki, Narita Kazuhiro, Tachimori Yuji, Goto Manabu
Department of Gastroenterological Surgery, Kawasaki Saiwai Hospital, Kanagawa, Japan.
Department of Pathology, Kawasaki Saiwai Hospital, Kanagawa, Japan.
Int J Surg Case Rep. 2019;60:111-114. doi: 10.1016/j.ijscr.2019.05.058. Epub 2019 Jun 11.
Extraskeletal osteosarcoma is a rare malignant soft tissue tumor without attachment to the bone. To the best of our knowledge, we present here the first report of a primary extraskeletal osteosarcoma of the mesentery in Japan.
A 46-year-old female underwent a health examination, with no complaint. Following an ultrasonography a solid mass was detected in the abdominal cavity. Computed tomography showed a 38 × 25 mm heterogeneously enhancing mass. The latter was characterized by the presence of mottled calcifications and a cystic portion. The tumor was resected with a single incisional laparoscopic curative resection. Histopathological examination revealed the presence of a primary extraskeletal osteosarcoma arising from the mesentery. Postoperative course was uneventful. The patient did not receive chemotherapy during follow-up. She was recurrence free 10 months post-surgery.
Patients with extraskeletal osteosarcoma generally have a poor prognosis. A tumor size <5 cm represents an important prognostic factor. Unexpectedly, our case was detected by ultrasonography at an early stage. This is the first report of a single incisional laparoscopic resection.
A primary extraskeletal osteosarcoma of the mesentery is an extremely rare occurrence. Its diagnosis should be taken into consideration also when a soft tissue mass of the mesentery is found.
骨外骨肉瘤是一种罕见的恶性软组织肿瘤,与骨无附着关系。据我们所知,本文报告了日本首例原发性肠系膜骨外骨肉瘤。
一名46岁女性接受健康检查,无不适主诉。超声检查后发现腹腔内有一实性肿块。计算机断层扫描显示一个38×25毫米的不均匀强化肿块。该肿块的特征是存在斑点状钙化和一个囊性部分。通过单切口腹腔镜根治性切除术切除肿瘤。组织病理学检查显示存在起源于肠系膜的原发性骨外骨肉瘤。术后病程平稳。患者在随访期间未接受化疗。术后10个月无复发。
骨外骨肉瘤患者的预后通常较差。肿瘤大小<5厘米是一个重要的预后因素。出乎意料的是,我们的病例通过超声检查在早期被发现。这是首例单切口腹腔镜切除术的报告。
原发性肠系膜骨外骨肉瘤极为罕见。当发现肠系膜软组织肿块时,也应考虑其诊断。