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妊娠期外阴癌:一例关于诊断、管理及手术结果的病例报告

Vulvar Carcinoma in Pregnancy: A Case Report on Diagnosis, Management, and Surgical Outcomes.

作者信息

Reddy Anitha, Donoori Swathi, Raju Kalidindi Venkata Vijaya Narsimha, Pogu Tejashwini

机构信息

Obstetrics and Gynaecology, Fernandez Hospital, Hyderabad, IND.

Surgical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, IND.

出版信息

Cureus. 2024 Dec 30;16(12):e76611. doi: 10.7759/cureus.76611. eCollection 2024 Dec.

DOI:10.7759/cureus.76611
PMID:39881917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11776030/
Abstract

Vulvar cancer is an uncommon malignancy in reproductive-aged women, and its occurrence during pregnancy is rare. This report presents a case of vulvar squamous cell carcinoma (VSCC) diagnosed perioperatively in a 35-year-old pregnant woman. The patient was incidentally found to have lichen sclerosis and a suspicious vulvar lesion during an emergency cesarean section. Biopsy confirmed VSCC, and subsequent management involved a simple vulvectomy, sentinel lymph node biopsy, and local advancement flap reconstruction. Histopathological examination revealed clear margins and no lymph node involvement. This case highlights the importance of routine external genital inspection during pregnancy to enable early detection and timely management of vulvar lesions.

摘要

外阴癌在育龄女性中是一种不常见的恶性肿瘤,在孕期发生则更为罕见。本报告介绍了一例在围手术期诊断为外阴鳞状细胞癌(VSCC)的35岁孕妇。该患者在急诊剖宫产术中偶然发现患有扁平苔藓硬化症及一处可疑外阴病变。活检确诊为VSCC,后续治疗包括单纯外阴切除术、前哨淋巴结活检及局部推进皮瓣重建术。组织病理学检查显示切缘清晰且无淋巴结受累。该病例强调了孕期常规外阴检查对于早期发现和及时处理外阴病变的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68fa/11776030/6ead6098d581/cureus-0016-00000076611-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68fa/11776030/48683b986e9c/cureus-0016-00000076611-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68fa/11776030/6ead6098d581/cureus-0016-00000076611-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68fa/11776030/48683b986e9c/cureus-0016-00000076611-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68fa/11776030/6ead6098d581/cureus-0016-00000076611-i02.jpg

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本文引用的文献

1
British Gynaecological Cancer Society (BGCS) vulval cancer guidelines: An update on recommendations for practice 2023.英国妇科癌症协会(BGCS)外阴癌指南:2023年实践建议更新
Eur J Obstet Gynecol Reprod Biol. 2024 Jan;292:210-238. doi: 10.1016/j.ejogrb.2023.11.013. Epub 2023 Nov 15.
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Risk of Development of Vulvar Cancer in Women With Lichen Sclerosus or Lichen Planus: A Systematic Review.外阴硬化性苔藓或扁平苔藓妇女发生外阴癌的风险:系统评价。
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Margins for cervical and vulvar cancer.宫颈癌和外阴癌的切缘
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Vulval and vaginal cancer in pregnancy.妊娠期外阴癌和阴道癌
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Vulvar cancer.外阴癌
Am Fam Physician. 2002 Oct 1;66(7):1269-74.