Trepczynski Adam, Kneifel Paul, Heyland Mark, Leskovar Marko, Moewis Philippe, Damm Philipp, Taylor William R, Zachow Stefan, Duda Georg N
Julius Wolff Institute, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.
Visual and Data-Centric Computing, Zuse Institute Berlin, Berlin, Germany.
Front Bioeng Biotechnol. 2025 Jan 15;12:1473951. doi: 10.3389/fbioe.2024.1473951. eCollection 2024.
Anterior knee pain and other patello-femoral (PF) complications frequently limit the success of total knee arthroplasty as the final treatment of end stage osteoarthritis. However, knowledge about the loading conditions at the PF joint remains limited, as no direct measurements are available. We hypothesised that the external knee flexion moment (EFM) is highly predictive of the PF contact forces during activities with substantial flexion of the loaded knee.
Six patients (65-80 years, 67-101 kg) with total knee arthroplasty (TKA) performed two activities of daily living: sit-stand-sit and squat. Tibio-femoral (TF) contact forces were measured using instrumented tibial components, while synchronously internal TF and PF kinematics were captured with mobile fluoroscopy. The measurements were used to compute PF contact forces using patient specific musculoskeletal models. The relationship between the EFM and the PF contact force was quantified using linear regression.
Mean peak TF contact forces of 1.97-3.24 times body weight (BW) were found while peak PF forces reached 1.75 to 3.29 times body weight (BW). The peak EFM ranged from 3.2 to 5.9 %BW times body height, and was a good predictor of the PF contact force ( = 0.95 and 0.88 for sit-stand-sit and squat, respectively).
The novel combination of TF contact forces and internal patellar kinematics enabled a reliable assessment of PF contact forces. The results of the regression analysis suggest that PF forces can be estimated based solely on the EFM from quantitative gait analysis. Our study also demonstrates the relevance of PF contact forces, which reach magnitudes similar to TF forces during activities of daily living.
前膝痛和其他髌股(PF)并发症常常限制全膝关节置换术作为终末期骨关节炎最终治疗手段的成功率。然而,由于无法进行直接测量,关于PF关节的负荷情况的了解仍然有限。我们假设,在负重膝关节大幅屈曲的活动中,外部膝关节屈曲力矩(EFM)能够高度预测PF接触力。
6例(年龄65 - 80岁,体重67 - 101 kg)接受全膝关节置换术(TKA)的患者进行了两项日常生活活动:坐 - 站 - 坐和深蹲。使用带仪器的胫骨组件测量胫股(TF)接触力,同时通过移动荧光透视同步采集TF和PF的内部运动学数据。利用患者特异性肌肉骨骼模型,将这些测量结果用于计算PF接触力。使用线性回归量化EFM与PF接触力之间的关系。
发现平均峰值TF接触力为体重(BW)的1.97 - 3.24倍,而峰值PF力达到体重(BW)的1.75至3.29倍。峰值EFM范围为3.2至5.9%BW×身高,并且是PF接触力的良好预测指标(坐 - 站 - 坐和深蹲的分别为 = 0.95和0.88)。
TF接触力与髌骨内部运动学的新颖结合能够可靠地评估PF接触力。回归分析结果表明,仅根据定量步态分析中的EFM就可以估计PF力。我们的研究还证明了PF接触力的相关性,其在日常生活活动中达到与TF力相似的量级。