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18F-多巴PET/CT在肿瘤学中的应用:韩国核医学学会操作指南

F-FDOPA PET/CT in Oncology: Procedural Guideline by the Korean Society of Nuclear Medicine.

作者信息

Park Yong-Jin, Choi Joon Ho, Lee Hyunjong, Moon Seung Hwan, Lee Inki, Lee Joohee, Yoo Jang, Choi Joon Young

机构信息

Department of Nuclear Medicine, Ajou University Medical Center, Ajou University School of Medicine, Suwon, Republic of Korea.

Department of Medical Sciences, Graduate School of Ajou University, Suwon, Republic of Korea.

出版信息

Nucl Med Mol Imaging. 2025 Feb;59(1):41-49. doi: 10.1007/s13139-024-00899-6. Epub 2024 Dec 20.

Abstract

This guideline outlines the use of 3,4-dihydroxy-6-F-fluoro-L-phenylalanine positron emission tomography / computed tomography for the diagnosis and management of neuroendocrine tumors, brain tumors, and other tumorous conditions. It provides detailed recommendations on patient preparation, imaging procedures, and result interpretation. Based on international standards and adapted to local clinical practices, the guideline emphasizes safety, quality control, and the effective application of 3,4-dihydroxy-6-F-fluoro-L-phenylalanine positron emission tomography / computed tomography for various tumors such as insulinomas, pheochromocytomas, and medullary thyroid carcinoma. It also addresses the use of premedication with carbidopa, fasting protocols, and optimal imaging techniques. The aim is to assist nuclear medicine professionals in delivering precise diagnoses, improving patient outcomes, and accommodating evolving medical knowledge and technology. This comprehensive document serves as a practical resource to enhance the accuracy, quality, and safety of 3,4-dihydroxy-6-F-fluoro-L-phenylalanine positron emission tomography / computed tomography in oncology.

摘要

本指南概述了3,4-二羟基-6-F-氟-L-苯丙氨酸正电子发射断层扫描/计算机断层扫描在神经内分泌肿瘤、脑肿瘤及其他肿瘤性疾病诊断和管理中的应用。它针对患者准备、成像程序及结果解读提供了详细建议。基于国际标准并结合当地临床实践,该指南强调了3,4-二羟基-6-F-氟-L-苯丙氨酸正电子发射断层扫描/计算机断层扫描在胰岛素瘤、嗜铬细胞瘤和甲状腺髓样癌等各种肿瘤中的安全性、质量控制及有效应用。它还涉及使用卡比多巴进行预处理、禁食方案及最佳成像技术。目的是协助核医学专业人员做出准确诊断、改善患者预后,并适应不断发展的医学知识和技术。这份全面的文件是提高3,4-二羟基-6-F-氟-L-苯丙氨酸正电子发射断层扫描/计算机断层扫描在肿瘤学中准确性、质量和安全性的实用资源。

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