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成人脊柱畸形的分期手术与同期手术:一项系统评价和荟萃分析

Staged Versus Simultaneous Surgery for Adult Spinal Deformity : A Systematic Review and Meta-analysis.

作者信息

Verma Aman, Bondarde Parshwanath, Kumar Anil, Sethy Siddharth Sekhar, Jain Aakash, Abrol Vibhor, Ahuja Kaustubh, Kandwal Pankaj

机构信息

Department of Orthopaedics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

出版信息

Spine (Phila Pa 1976). 2025 Jun 15;50(12):859-870. doi: 10.1097/BRS.0000000000005279. Epub 2025 Jan 30.

Abstract

STUDY DESIGN

Systematic review and meta-analysis.

OBJECTIVE

To assess the safety and efficacy of staged versus same-day spinal fusion surgeries in adult spinal deformity (ASD).

BACKGROUND

ASD surgeries are associated with high complication rates, ranging from 10% to 40%. Among the strategies to enhance safety, staging the procedure into two smaller procedures has been evaluated as an effective alternative.

MATERIALS AND METHODS

A systematic literature review following PRISMA guidelines was conducted using PubMed, Cochrane, Scopus, and Embase. Studies comparing staged and same-day spinal fusion for ASD were included. Perioperative data, patient-reported outcomes (ODI, SRS), radiologic outcomes, and complication rates were analyzed. The extracted data was analyzed, and forest plots were generated to draw comparisons between the staged and same-day groups.

RESULTS

Eleven studies, including 1323 patients (541 staged, 782 same-day) were analyzed. Staged surgeries were associated with longer operative time and length of hospital stay. There was no significant difference in estimated blood loss, clinical and radiologic outcomes, or overall complication rates between groups. However, venous thromboembolism (VTE) rates were significantly higher in staged surgeries (odds ratio=4.33). In the staged group, surgical site infections were the most common complication, with a rate of 10.5%, whereas neurological complications were the most frequent group of complications in the same-day group.

CONCLUSION

Staged surgeries for ASD result in longer operative time, length of hospital stay, and increased VTE risk but show similar efficacy in clinical and radiologic outcomes compared with same-day surgeries. Careful patient selection is crucial to balance risks and optimize outcomes in ASD surgical planning.

摘要

研究设计

系统评价与荟萃分析。

目的

评估分期与同日进行的脊柱融合手术治疗成人脊柱畸形(ASD)的安全性和有效性。

背景

ASD手术的并发症发生率较高,在10%至40%之间。在提高安全性的策略中,将手术分两期进行两个较小的手术已被评估为一种有效的替代方法。

材料与方法

按照PRISMA指南,使用PubMed、Cochrane、Scopus和Embase进行系统的文献综述。纳入比较分期与同日进行脊柱融合治疗ASD的研究。分析围手术期数据、患者报告的结局(ODI、SRS)、放射学结局和并发症发生率。对提取的数据进行分析,并生成森林图以比较分期组和同日组。

结果

分析了11项研究,包括1323例患者(541例分期手术,782例同日手术)。分期手术的手术时间和住院时间较长。两组之间的估计失血量、临床和放射学结局或总体并发症发生率无显著差异。然而,分期手术的静脉血栓栓塞(VTE)发生率显著更高(优势比=4.33)。在分期组中,手术部位感染是最常见的并发症,发生率为10.5%,而神经并发症是同日组中最常见的并发症类型。

结论

ASD的分期手术导致手术时间更长、住院时间更长以及VTE风险增加,但与同日手术相比,在临床和放射学结局方面显示出相似的疗效。在ASD手术规划中,仔细选择患者对于平衡风险和优化结局至关重要。

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