Meisel Samuel, Porter Nicole, Bobek Molly, Henderson Craig E, Hogue Aaron
Department of Psychological and Brain Sciences, Boston University.
Research and Clinical Science, Partnership to End Addiction.
J Clin Child Adolesc Psychol. 2025 Jan 30:1-15. doi: 10.1080/15374416.2025.2454640.
Changing Academic Support in the Home for Adolescents with ADHD (CASH-AA) and Medication Integration Protocol (MIP) are two family-based behavioral protocols designed to promote family solutions to academic problems and medication decision-making. Building on a randomized control trial examining these protocols, the current study examined how protocol dose, an indicator of treatment adherence, was associated with treatment outcomes.
The sample consisted of 145 adolescent clients (M age = 14.8, 72% male, 42% White, 37% Hispanic, 15% Black) and 49 community and hospital-based therapists (82% female, 63% White, 29% Hispanic). Latent growth curve models examined how therapist reports of minutes adolescents and their caregivers received CASH-AA and MIP predicted levels and change in inattentive and hyperactive symptoms (MINI-International Neuropsychiatric Interview); co-occurring symptoms (Youth Self Report/Child Behavior Checklist); homework problems (Homework Problems Checklist); and medication compliance at baseline, 3, 6, and 12-month follow-ups.
MIP minutes were prospectively associated with lower caregiver-reported inattentive and hyperactive symptoms, adolescent- and caregiver-reported externalizing symptoms and caregiver-reported homework problems at the 12-month follow-up (ẞ range = -.16 to -.39, < .05), as well as faster decline in caregiver-reported inattentive symptoms (ẞ = -.29, < .001). CASH-AA minutes were associated with greater caregiver-reported inattentive symptoms (ẞ = .11, = .049) at 12-month follow-up and slower declines in homework problems (ẞ = -.39, < .001). Neither MIP nor CASH-AA minutes were associated with internalizing symptoms or medication use.
Findings further support MIP as an effective behavioral protocol for adolescent ADHD and indicate the need for increasing MIP implementation efforts in community settings.
家庭中为多动症青少年改变学业支持(CASH - AA)和药物整合方案(MIP)是两个基于家庭的行为方案,旨在促进家庭解决学业问题和药物决策。基于一项检验这些方案的随机对照试验,本研究考察了方案剂量(治疗依从性的一个指标)与治疗结果之间的关联。
样本包括145名青少年客户(平均年龄 = 14.8岁,72%为男性,42%为白人,37%为西班牙裔,15%为黑人)以及49名社区和医院的治疗师(82%为女性,63%为白人,29%为西班牙裔)。潜在增长曲线模型考察了治疗师报告的青少年及其照顾者接受CASH - AA和MIP的时长如何预测在基线、3个月、6个月和12个月随访时注意力不集中和多动症状(MINI国际神经精神访谈)、共病症状(青少年自我报告/儿童行为清单)、家庭作业问题(家庭作业问题清单)以及药物依从性的水平和变化。
在12个月随访时,MIP时长与照顾者报告的较低的注意力不集中和多动症状、青少年和照顾者报告的外化症状以及照顾者报告的家庭作业问题呈前瞻性关联(β范围 = -0.16至 -0.39,P < 0.05),同时与照顾者报告的注意力不集中症状的更快下降相关(β = -0.29,P < 0.001)。在12个月随访时,CASH - AA时长与照顾者报告的更严重的注意力不集中症状相关(β = 0.11,P = 0.049),且与家庭作业问题的下降较慢相关(β = -0.39,P < 0.001)。MIP和CASH - AA时长均与内化症状或药物使用无关。
研究结果进一步支持MIP作为青少年多动症的有效行为方案,并表明需要在社区环境中加大MIP的实施力度。