Regev-Avraham Zipi, Rozenfeld Ina, Hussein Osamah, Sharabi-Nov Adi, Halabi Majdi
Intensive Cardiac Care Department, Ziv Medical Center.
Nursing Department, Zefat Academic College.
Coron Artery Dis. 2025 Aug 1;36(5):373-377. doi: 10.1097/MCA.0000000000001477. Epub 2025 Jan 31.
Coronary artery calcium, a marker of coronary atherosclerosis, is often identified on noncoronary chest computed tomography (CT). We wanted to evaluate the correlation between the presence of coronary plaques in coronary artery catheterization and coronary calcifications as shown in noncardiac chest CT.
A retrospective case-control study consisting of cases ( N = 63) and controls ( N = 29), aged 18-70 years old, residing in northern Israel and treated in the Intensive Cardiac Care Unit of Ziv Medical Center, between January 2020 and November 2022. All participants underwent coronary catheterization and noncoronary CT scans in the 5 years before the catheterization procedure. Data were taken from the participants' electronic files while considering the potential of cardiovascular risk factors.
The 92 participants had a mean age of 60.1 ± 10.3 years old. Multivariate logistic regression adjusted to age, sex, and hyperlipidemia showed that calcified coronary artery as shown on a previous noncardiac CT scan was positively and significantly associated with increasing risk of coronary plaque as presented in coronary catheterization: odds ratio = 5.93 (95% confidence interval: 1.85-19.07, P < 0.01) and was also associated with male sex who were more likely to have plaque on coronary catheterization than females: odds ratio = 3.77 (95% confidence interval: 1.29-11.32, P < 0.05).
Coronary calcifications on a previous noncoronary CT scan and sex are positively and significantly associated with coronary plaque risk as present in coronary catheterization. Coronary evaluation on CT scans is important for early detection of coronary disease. Early treatment can avoid coronary disease complications and increase patient survival.
冠状动脉钙化是冠状动脉粥样硬化的一个标志物，常在非冠状动脉胸部计算机断层扫描（CT）中被发现。我们想要评估冠状动脉导管插入术中冠状动脉斑块的存在与非心脏胸部CT所示冠状动脉钙化之间的相关性。
一项回顾性病例对照研究，研究对象为2020年1月至2022年11月期间居住在以色列北部、在齐夫医疗中心重症心脏监护病房接受治疗的18至70岁的病例（N = 63）和对照（N = 29）。所有参与者在导管插入术之前的5年内均接受了冠状动脉导管插入术和非冠状动脉CT扫描。在考虑心血管危险因素的可能性时，从参与者的电子档案中获取数据。
92名参与者的平均年龄为60.1±10.3岁。经年龄、性别和高脂血症校正的多因素逻辑回归显示，先前非心脏CT扫描所示的钙化冠状动脉与冠状动脉导管插入术中冠状动脉斑块风险增加呈正相关且具有显著相关性：比值比 = 5.93（95%置信区间：1.85 - 19.07，P < 0.01），并且还与男性相关，男性在冠状动脉导管插入术中比女性更有可能出现斑块：比值比 = 3.77（95%置信区间：1.29 - 11.32，P < 0.05）。
先前非冠状动脉CT扫描上的冠状动脉钙化和性别与冠状动脉导管插入术中存在的冠状动脉斑块风险呈正相关且具有显著相关性。CT扫描上的冠状动脉评估对于早期发现冠状动脉疾病很重要。早期治疗可以避免冠状动脉疾病并发症并提高患者生存率。
