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探索分诊阶段快乐低氧血症与2019冠状病毒病之间的关联。

Exploring the association between happy hypoxia and Coronavirus disease 2019 in the triage phase.

作者信息

Kaga Mihiro, Sasaki Masanao, Masuda Takahiro, Sato Hiroyuki, Ueda Takeshi, Hirakawa Akihiro

机构信息

Department of Clinical Biostatistics, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.

Emergency and General Internal Medicine, Rakuwakai Marutamachi Hospital, Kyoto, Japan.

出版信息

Future Sci OA. 2025 Dec;11(1):2458413. doi: 10.1080/20565623.2025.2458413. Epub 2025 Jan 30.

Abstract

BACKGROUND

Patients with severe coronavirus disease 2019 (COVID-19) have been reported to show hypoxia without displaying typical clinical signs or symptoms, called "happy hypoxia." To explore the potential of happy hypoxia as a distinctive symptom of COVID-19, we compared vital signs in the triage phase between patients with and without COVID-19.

METHODS

We retrospectively identified emergency patients with and without COVID-19 admitted to Rakuwakai Marutamachi Hospital, Kyoto, Japan, between January 2021 and December 2021.

RESULTS AND CONCLUSIONS

317 patients were analyzed. Multivariate logistic regression analysis, including all vital signs, demonstrated that the respiratory rate was not statistically associated with COVID-19 (odds ratio, 0.94, p = 0.058), suggesting that happy hypoxia may not be a distinct hallmark of COVID-19.

摘要

背景

据报道,患有严重2019冠状病毒病(COVID-19)的患者会出现缺氧症状,但未表现出典型的临床体征或症状,即所谓的“快乐缺氧”。为了探究快乐缺氧作为COVID-19独特症状的可能性,我们比较了COVID-19患者和非COVID-19患者在分诊阶段的生命体征。

方法

我们回顾性地确定了2021年1月至2021年12月期间入住日本京都乐和会丸太町医院的有或没有COVID-19的急诊患者。

结果与结论

共分析了317例患者。包括所有生命体征的多变量逻辑回归分析表明,呼吸频率与COVID-19无统计学关联(比值比,0.94;p = 0.058),这表明快乐缺氧可能不是COVID-19的明显特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f3f/11792821/61ecd1233144/IFSO_A_2458413_F0001_C.jpg

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