多虑平导致胃排空延迟。
Delayed gastric emptying with dothiepin.
作者信息
Woodhouse K W, Bateman D N
出版信息
Hum Toxicol. 1985 Jan;4(1):67-70. doi: 10.1177/096032718500400108.
PMID:3988307
Abstract
Dothiepin induced symptoms of delayed gastric emptying in an elderly lady. Rechallenge studies were undertaken and demonstrated a delay in gastric emptying of liquid after re-administration of dothiepin at a time when plasma concentrations were 93 micrograms/l. Elderly patients may be more susceptible to the anticholinergic effects of tricyclic antidepressants on the gut.
摘要
多虑平在一位老年女性中诱发了胃排空延迟的症状。进行了再激发研究，结果表明在血浆浓度为93微克/升时再次给予多虑平后，液体胃排空出现延迟。老年患者可能对三环类抗抑郁药对肠道的抗胆碱能作用更敏感。
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