Aglan H, Ali I A, Ali B M, Kandil S A
Cyclotron Facility, Nuclear Research Center, Egyptian Atomic Energy Authority, Cairo, Egypt.
Labeled Compounds Department, Hot Labs. Center, Egyptian Atomic Energy Authority, Cairo, Egypt.
J Mater Sci Mater Med. 2025 Jan 30;36(1):17. doi: 10.1007/s10856-025-06859-6.
This study aimed to synthesize MgFeLnO (where, Ln = Yb, Pr, Gd, and Nd) ferrite nanoparticles via the sol-gel process and investigate their structural, morphological, and magnetic properties for potential hyperthermia applications. X-ray diffraction analysis (XRD) confirmed the cubic spinel structure for all samples. Transmission electron microscopy (TEM) images revealed nanometer-scale dimensions and nearly spherical morphology. Vibrating sample magnetometer measurements (VSM) indicated superparamagnetic behavior, with decreasing saturation magnetization (Ms) observed as Ln content decreased. Specific absorption rate (SAR) analysis at 198 kHz demonstrated the influence of Ln substitution on magnetic properties. Compared to existing studies, Ln substituted (Yb, Pr, Gd, and Nd) nanoparticles demonstrate tunable magnetic properties and enhanced SAR performance, offering a more efficient design for hyperthermia treatment of solid tumors.
本研究旨在通过溶胶-凝胶法合成MgFeLnO（其中，Ln = Yb、Pr、Gd和Nd）铁氧体纳米颗粒，并研究其结构、形态和磁性，以用于潜在的热疗应用。X射线衍射分析（XRD）证实了所有样品的立方尖晶石结构。透射电子显微镜（TEM）图像显示出纳米级尺寸和近乎球形的形态。振动样品磁强计测量（VSM）表明存在超顺磁行为，随着Ln含量的降低，饱和磁化强度（Ms）也随之降低。在198 kHz下的比吸收率（SAR）分析表明了Ln取代对磁性的影响。与现有研究相比，Ln取代（Yb、Pr、Gd和Nd）的纳米颗粒表现出可调谐的磁性和增强的SAR性能，为实体瘤的热疗提供了更有效的设计。
