Edwards Emily R, Geraci Joseph C, Gildea Sarah M, Houtsma Claire, Holdcraft Jacob A, Kennedy Chris J, King Andrew J, Luedtke Alex, Marx Brian P, Naifeh James A, Sampson Nancy A, Stein Murray B, Ursano Robert J, Kessler Ronald C
VISN 2 MIRECC, Department of Veterans Affairs, Bronx, NY, USA.
Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Transl Psychiatry. 2025 Jan 30;15(1):37. doi: 10.1038/s41398-025-03248-z.
Risk of U.S. Army soldier suicide-related behaviors increases substantially after separation from service. As universal prevention programs have been unable to resolve this problem, a previously reported machine learning model was developed using pre-separation predictors to target high-risk transitioning service members (TSMs) for more intensive interventions. This model is currently being used in a demonstration project. The model is limited, though, in two ways. First, the model was developed and trained in a relatively small cross-validation sample (n = 4044) and would likely be improved if a larger sample was available. Second, the model provides no guidance on subtyping high-risk TSMs. This report presents results of an attempt to refine the model to address these limitations by re-estimating the model in a larger sample (n = 5909) and attempting to develop embedded models for differential risk of post-separation stressful life events (SLEs) known to mediate the association of model predictions with post-separation nonfatal suicide attempts (SAs; n = 4957). Analysis used data from the Army STARRS Longitudinal Surveys. The revised model improved prediction of post-separation SAs in the first year (AUC = 0.85) and second-third years (AUC = 0.77) after separation, but embedded models could not predict post-separation SLEs with enough accuracy to support intervention targeting.
美国陆军士兵退役后与自杀相关行为的风险大幅增加。由于通用预防计划未能解决这一问题,之前报道的一个机器学习模型利用退役前的预测因素来确定高风险过渡服役人员(TSM),以便进行更密集的干预。该模型目前正在一个示范项目中使用。不过,该模型在两个方面存在局限性。首先,该模型是在一个相对较小的交叉验证样本(n = 4044)中开发和训练的,如果有更大的样本,可能会有所改进。其次,该模型没有提供对高风险TSM进行亚型分类的指导。本报告介绍了为解决这些局限性而对模型进行改进的尝试结果,即在一个更大的样本(n = 5909)中重新估计模型,并尝试开发嵌入式模型,以区分已知介导模型预测与退役后非致命自杀未遂(SA;n = 4957)之间关联的退役后应激生活事件(SLE)的不同风险。分析使用了陆军STARRS纵向调查的数据。修订后的模型在退役后的第一年(AUC = 0.85)和第二至三年(AUC = 0.77)对退役后SA的预测有所改善,但嵌入式模型无法以足够的准确性预测退役后的SLE,以支持有针对性的干预。