Malek Angela M, Wen Chun-Che, Neelon Brian, Wilson Dulaney A, Mateus Julio, Pearce John, Simpson Sarah, Chundru Kalyan, Korte Jeffrey E, Florez Hermes, Finneran Matthew, Alkis Mallory, Hunt Kelly J
Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.
Health Equity and Rural Outreach Innovation Center, Ralph H. Johnson Department of Veterans Affairs Medical Center, Charleston, South Carolina, USA.
Women Health. 2025 Feb;65(2):182-196. doi: 10.1080/03630242.2025.2457641. Epub 2025 Jan 30.
Hypertensive disorders of pregnancy (HDP) and chronic hypertension (CHTN) are related to maternal and infant morbidity and mortality. We aimed to assess HDP and CHTN prevalence changes before (January 2015-February 2020) and during the COVID-19 pandemic (March 2020-December 2021) in South Carolina (SC). SC live births (2015-2021) were included (194,841 non-Hispanic White [NHW]); 108,195 non-Hispanic Black [NHB]; 25,560 Hispanic; 16,346 other race/ethnicity). Linked birth certificate and hospitalization/ED data was used. Relative risks (RRs) and 95 percent CIs adjusted for potential confounders estimated HDP and CHTN risk before and during the pandemic. HDP risk is associated with a one-year increase in calendar time pre-pandemic differed by race/ethnicity. Corresponding RRs (95 percent CIs) were 1.06 (1.05-1.06) in NHW, 1.07 (1.06-1.07) in NHB, 1.07 (1.06-1.09) in Hispanic and 1.09 (1.07-1.12) for other races/ethnicities. During the pandemic, RRs (95 percent CIs) attenuated slightly remaining significant (NHW, 1.03 [1.01-1.04]; NHB, 1.04 [1.02-1.05]; Hispanic, 1.04 [1.02-1.07]; other races/ethnicities, 1.06 [1.04-1.09]). Increasing race-ethnic group-specific trends from 2015 to 2021 were reported for CHTN (NHW, 1.09 [1.08-1.10]; NHB, 1.09 [1.08-1.10]; Hispanic, 1.08 [1.05-1.12]; other races/ethnicities, 1.15 [1.11-1.19]). HDP and CHTN's increasing prevalence from 2015 to 2021 differed by race/ethnicity, with HDP impacted by the pandemic and upward trends observed for both conditions after adjustment. Screening, diagnostic, and reporting practices across different data sources and actual changes may impact HDP and CHTN prevalence.
妊娠高血压疾病（HDP）和慢性高血压（CHTN）与母婴发病率和死亡率相关。我们旨在评估南卡罗来纳州（SC）在2015年1月至2020年2月之前以及2019冠状病毒病大流行期间（2020年3月至2021年12月）HDP和CHTN患病率的变化。纳入了SC的活产数据（2015 - 2021年）（194,841名非西班牙裔白人[NHW]；108,195名非西班牙裔黑人[NHB]；25,560名西班牙裔；16,346名其他种族/族裔）。使用了关联的出生证明和住院/急诊数据。针对潜在混杂因素调整后的相对风险（RRs）和95%置信区间估计了大流行之前和期间HDP和CHTN的风险。大流行前HDP风险与日历时间每年增加相关，且因种族/族裔而异。相应的RRs（95%置信区间）在NHW中为1.06（1.05 - 1.06），在NHB中为1.07（1.06 - 1.07），在西班牙裔中为1.07（1.06 - 1.09），在其他种族/族裔中为1.09（1.07 - 1.12）。在大流行期间，RRs（95%置信区间）略有减弱但仍具有显著性（NHW，1.03 [（1.01 - 1.04）]；NHB，1.04 [1.02 - 1.05]；西班牙裔，1.04 [1.02 - 1.07]；其他种族/族裔，1.06 [1.04 - 1.09]）。报告了2015年至2021年CHTN种族/族裔组特异性趋势增加（NHW，1.09 [1.08 - 1.10]；NHB，1.09 [1.08 - 1.10]；西班牙裔，1.08 [1.05 - 1.12]；其他种族/族裔，1.15 [1.11 - 1.19]）。2015年至2021年HDP和CHTN患病率增加因种族/族裔而异，HDP受大流行影响，调整后两种情况均观察到上升趋势。不同数据源的筛查、诊断和报告实践以及实际变化可能会影响HDP和CHTN的患病率。
