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Case Study 8: A 70-Year-Old Man With Memory Loss, Wandering, and Inappropriate Behaviors.

作者信息

Gibson Lakeshia C, Krause Katherine A, Gale Seth A, Schildkrout Barbara, Miller Michael B, Feany Mel B, Silbersweig David A, Daffner Kirk R, Yang Hyun-Sik, McGinnis Scott M

机构信息

Departments of Psychiatry (Gibson, Schildkrout, Silbersweig) and Neurology (Gale, Daffner, Yang, McGinnis), Center for Brain/Mind Medicine, and Department of Pathology (Krause, Miller, Feany), Brigham and Women's Hospital, Harvard Medical School, Boston.

出版信息

J Neuropsychiatry Clin Neurosci. 2025 Summer;37(3):222-229. doi: 10.1176/appi.neuropsych.20240125. Epub 2025 Jan 31.

DOI:10.1176/appi.neuropsych.20240125
PMID:39885722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12213165/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3db/12213165/5819a636f747/nihms-2064308-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3db/12213165/147207aa569e/nihms-2064308-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3db/12213165/5819a636f747/nihms-2064308-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3db/12213165/147207aa569e/nihms-2064308-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3db/12213165/5819a636f747/nihms-2064308-f0002.jpg

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本文引用的文献

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Case Study 6: The Diagnostic Challenge of a 75-Year-Old Man Who Had, Then Didn't Have, Then Did Have Alzheimer's Disease.病例研究6:一位75岁男性患者的诊断难题,该患者曾被诊断患有、后又未被诊断患有、最后又被诊断患有阿尔茨海默病。
J Neuropsychiatry Clin Neurosci. 2023 Fall;35(4):325-332. doi: 10.1176/appi.neuropsych.20230097.
2
Clinical characteristics of pathological confirmed prodromal dementia with Lewy bodies.经病理证实的路易体前驱期痴呆的临床特征。
J Neurol Sci. 2023 Oct 15;453:120815. doi: 10.1016/j.jns.2023.120815. Epub 2023 Sep 21.
3
Case Study 5: A 74-Year-Old Man With Dysphagia, Weakness, and Memory Loss.
病例研究5:一名74岁男性,伴有吞咽困难、虚弱和记忆力减退。
J Neuropsychiatry Clin Neurosci. 2023 Summer;35(3):210-217. doi: 10.1176/appi.neuropsych.20230030.
4
Morphological characteristics differentiate dementia with Lewy bodies from Parkinson disease with and without dementia.形态学特征可将路易体痴呆与伴有和不伴有痴呆的帕金森病区分开来。
J Neural Transm (Vienna). 2023 Jul;130(7):891-904. doi: 10.1007/s00702-023-02660-3. Epub 2023 Jun 12.
5
Tightened Sulci in the High Convexities as a Noteworthy Feature of Idiopathic Normal Pressure Hydrocephalus.脑回增宽在特发性正常压力脑积水的一个显著特征。
World Neurosurg. 2023 Aug;176:e427-e437. doi: 10.1016/j.wneu.2023.05.077. Epub 2023 May 26.
6
MRI-based basal forebrain atrophy and volumetric signatures associated with limbic TDP-43 compared to Alzheimer's disease pathology.基于 MRI 的基底前脑萎缩和与额颞叶痴呆(TDP-43 相关)相比与阿尔茨海默病病理相关的容积特征。
Neurobiol Dis. 2023 May;180:106070. doi: 10.1016/j.nbd.2023.106070. Epub 2023 Mar 8.
7
Early-stage differentiation between Alzheimer's disease and frontotemporal lobe degeneration: Clinical, neuropsychology, and neuroimaging features.阿尔茨海默病与额颞叶痴呆的早期鉴别:临床、神经心理学及神经影像学特征
Front Aging Neurosci. 2022 Oct 31;14:981451. doi: 10.3389/fnagi.2022.981451. eCollection 2022.
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Symptomatic Profile and Cognitive Performance in Autopsy-Confirmed Limbic-Predominant Age-Related TDP-43 Encephalopathy With Comorbid Alzheimer Disease.尸检证实的伴有阿尔茨海默病共病的边缘为主型年龄相关性 TDP-43 脑病的症状谱和认知表现。
J Neuropathol Exp Neurol. 2022 Nov 16;81(12):975-987. doi: 10.1093/jnen/nlac093.
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Limbic-Predominant Age-Related TDP-43 Encephalopathy: LATE-Breaking Updates in Clinicopathologic Features and Biomarkers.边缘系统为主型年龄相关性 TDP-43 脑病:临床病理特征和生物标志物的最新突破。
Curr Neurol Neurosci Rep. 2022 Nov;22(11):689-698. doi: 10.1007/s11910-022-01232-4. Epub 2022 Oct 3.