Kaur Gagandeep, Banaag Shanley, Hong Lee, Mylavarapu Charisma, Kim Yuri, Garrett John, Nagler Emily
Scripps Mercy Hospital San Diego California USA.
Scripps Clinic Medical Group San Diego California USA.
Clin Case Rep. 2025 Jan 29;13(2):e70102. doi: 10.1002/ccr3.70102. eCollection 2025 Feb.
In patients with severe refractory immune thrombocytopenia (ITP), especially those unable to receive blood transfusions due to religious beliefs, alternative non-cytotoxic therapies are important to avoid worsening cytopenias. Immunomodulatory agents such as mycophenolate mofetil and daratumumab should be used alongside traditional therapies including steroids, IVIG and rituximab.
在重度难治性免疫性血小板减少症(ITP)患者中,尤其是那些因宗教信仰而无法接受输血的患者,采用替代性非细胞毒性疗法对于避免血细胞减少症恶化非常重要。免疫调节剂,如霉酚酸酯和达雷妥尤单抗,应与包括类固醇、静脉注射免疫球蛋白(IVIG)和利妥昔单抗在内的传统疗法联合使用。