对X. Wang、D.-K. Kong、H.-R. Zhang、Y. Zou等人于2024年发表的《通过β-葡萄糖苷酶介导的酯键水解从聚酮糖苷杂化物中发现聚酮羧酸盐植物毒素》的评论，17183
Comment on "Discovery of a polyketide carboxylate phytotoxin from a polyketide glycoside hybrid by β-glucosidase mediated ester bond hydrolysis" by X. Wang, D.-K. Kong, H.-R. Zhang, Y. Zou, , 2024, , 17183.
作者信息
Nasseri Seyed Amirhossein, Bains Rajneesh K, Tian Yuqing, Withers Stephen G
机构信息
Department of Chemistry, University of British Columbia Vancouver Canada
Michael Smith Laboratories, University of British Columbia Vancouver Canada.
出版信息
Chem Sci. 2025 Jan 28;16(8):3755-3757. doi: 10.1039/d4sc07749k. eCollection 2025 Feb 19.
Abstract
We challenge the conclusion that the β-glucosidase in question directly catalyses hydrolysis of the substrate ester linkage. Rather we propose that this enzyme performs a normal glucoside hydrolysis and that the released aglycone undergoes rearrangement with formation of a quinone methide-like species through spontaneous cleavage of the ester.
摘要
我们对关于所讨论的β-葡萄糖苷酶直接催化底物酯键水解的结论提出质疑。相反，我们认为该酶进行正常的糖苷水解，并且释放出的苷元通过酯的自发裂解发生重排，形成类似醌甲基化物的物种。
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本文引用的文献
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