Lent-Schochet Daniella, Akbar Mizna, Hou Joshua H, Farooq Asim V
Department of Ophthalmology and Visual Science, University of Chicago, Chicago, IL, United States.
Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minnesota, MN, United States.
Front Ophthalmol (Lausanne). 2025 Jan 16;4:1524595. doi: 10.3389/fopht.2024.1524595. eCollection 2024.
Limbal stem cell deficiency (LSCD) is an important cause of visual and ocular morbidity. Effective diagnosis and management require a thoughtful and comprehensive evaluation of the ocular surface. This review describes the pathogenesis, diagnosis, and grading of LSCD, as well as characteristic findings via slit lamp examination, confocal microscopy, anterior segment optical coherence tomography (AS-OCT), impression cytology, and OCT angiography.
角膜缘干细胞缺乏（LSCD）是导致视力下降和眼部病变的重要原因。有效的诊断和治疗需要对眼表进行细致全面的评估。本文综述了LSCD的发病机制、诊断和分级，以及通过裂隙灯检查、共焦显微镜检查、眼前节光学相干断层扫描（AS-OCT）、印迹细胞学检查和OCT血管造影的特征性表现。
