Beckner M, Berg J W, Franz L W
J Chronic Dis. 1985;38(3):225-31. doi: 10.1016/0021-9681(85)90065-7.
In order to quantitate the contribution of latent prostatic cancer to the very high prostatic cancer incidence rate in Denver, we conducted a population-based study. In 1979, 33% of 402 incidence cases were discovered incidentally, 4% at autopsy and 29% because of surgery for presumably benign prostatic disease. Of the unsuspected cases, 43% were stage A1, i.e. low grade and focal. The rest were high grade, more extensive, or both. It is expected that unsuspected cancers are a highly variable component of reported rates of prostatic cancer from other areas since their frequency of discovery depends upon urological and pathological practices that have been demonstrated to vary greatly from region to region.
为了量化潜伏性前列腺癌对丹佛市极高前列腺癌发病率的影响，我们开展了一项基于人群的研究。1979年，402例前列腺癌发病病例中，33%是偶然发现的，4%是在尸检时发现的，29%是因疑似良性前列腺疾病而接受手术时发现的。在未被怀疑的病例中，43%为A1期，即低级别且病灶局限。其余病例为高级别、范围更广或两者皆有。由于未被怀疑的癌症被发现的频率取决于泌尿外科和病理学实践，而这些实践已被证明在不同地区差异很大，所以预计未被怀疑的癌症是其他地区报告的前列腺癌发病率中一个高度可变的组成部分。
