• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

儿科神经学中的可穿戴传感器

Wearable sensors in paediatric neurology.

作者信息

González Barral Camila, Servais Laurent

机构信息

Sysnav, Vernon, France.

Neuromuscular Reference Center, Department of Pediatrics, University Hospital Liège, Belgium.

出版信息

Dev Med Child Neurol. 2025 Jul;67(7):834-853. doi: 10.1111/dmcn.16239. Epub 2025 Jan 31.

DOI:10.1111/dmcn.16239
PMID:39888848
Abstract

Wearable sensors have the potential to transform diagnosis, monitoring, and management of children who have neurological conditions. Traditional methods for assessing neurological disorders rely on clinical scales and subjective measures. The snapshot of the disease progression at a particular time point, lack of cooperation by the children during assessments, and susceptibility to bias limit the utility of these measures. Wearable sensors, which capture data continuously in natural settings, offer a non-invasive and objective alternative to traditional methods. This review examines the role of wearable sensors in various paediatric neurological conditions, including cerebral palsy, epilepsy, autism spectrum disorder, attention-deficit/hyperactivity disorder, as well as Rett syndrome, Down syndrome, Angelman syndrome, Prader-Willi syndrome, neuromuscular disorders such as Duchenne muscular dystrophy and spinal muscular atrophy, ataxia, Gaucher disease, headaches, and sleep disorders. The review highlights their application in tracking motor function, seizure activity, and daily movement patterns to gain insights into disease progression and therapeutic response. Although challenges related to population size, compliance, ethics, and regulatory approval remain, wearable technology promises to improve clinical trials and outcomes for patients in paediatric neurology.

摘要

可穿戴传感器有潜力改变对患有神经疾病儿童的诊断、监测和管理方式。评估神经疾病的传统方法依赖于临床量表和主观测量。特定时间点疾病进展的快照、儿童在评估期间缺乏配合以及易受偏差影响,限制了这些测量方法的效用。可穿戴传感器能在自然环境中持续捕捉数据,为传统方法提供了一种非侵入性且客观的替代方案。本综述探讨了可穿戴传感器在各种儿科神经疾病中的作用,包括脑瘫、癫痫、自闭症谱系障碍、注意力缺陷多动障碍,以及雷特综合征、唐氏综合征、天使综合征、普拉德 - 威利综合征、神经肌肉疾病如杜氏肌营养不良症和脊髓性肌萎缩症、共济失调、戈谢病、头痛和睡眠障碍。该综述强调了它们在追踪运动功能、癫痫活动和日常运动模式以深入了解疾病进展和治疗反应方面的应用。尽管与样本量、依从性、伦理和监管批准相关的挑战仍然存在,但可穿戴技术有望改善儿科神经病学患者的临床试验和治疗结果。

相似文献

1
Wearable sensors in paediatric neurology.儿科神经学中的可穿戴传感器
Dev Med Child Neurol. 2025 Jul;67(7):834-853. doi: 10.1111/dmcn.16239. Epub 2025 Jan 31.
2
Feasibility of wearable technology for 'real-world' gait analysis in children with Prader-Willi and Angelman syndromes.可穿戴技术在 Prader-Willi 和 Angelman 综合征患儿“真实世界”步态分析中的可行性。
J Intellect Disabil Res. 2022 Aug;66(8-9):717-725. doi: 10.1111/jir.12955. Epub 2022 Jun 17.
3
Motor function testing rates and outcomes in Duchenne muscular dystrophy with comorbid autism and attention-deficit/hyperactivity disorder.杜氏肌营养不良症合并自闭症和注意力缺陷多动障碍时的运动功能测试率及结果
Neuromuscul Disord. 2025 Mar;48:105281. doi: 10.1016/j.nmd.2025.105281. Epub 2025 Jan 30.
4
Stride Velocity 95th Centile: Insights into Gaining Regulatory Qualification of the First Wearable-Derived Digital Endpoint for use in Duchenne Muscular Dystrophy Trials.步速第 95 百分位:在杜氏肌营养不良症试验中获得首款可穿戴衍生数字终点的监管资格的见解。
J Neuromuscul Dis. 2022;9(2):335-346. doi: 10.3233/JND-210743.
5
Wearable Sensors and Motion Analysis for Neurological Patient Support.用于神经科患者支持的可穿戴传感器与运动分析
Biosensors (Basel). 2024 Dec 19;14(12):628. doi: 10.3390/bios14120628.
6
Wearable Sensors for Ensuring Sports Safety in Children with Autism Spectrum Disorder: A Comprehensive Review.用于确保自闭症谱系障碍儿童运动安全的可穿戴传感器:综述
Sensors (Basel). 2025 Feb 26;25(5):1409. doi: 10.3390/s25051409.
7
Wearable sensors for measuring spontaneous upper limb use in children with unilateral cerebral palsy and typical development.用于测量单侧脑瘫和发育正常儿童自发上肢使用情况的可穿戴传感器。
J Neuroeng Rehabil. 2025 Apr 3;22(1):71. doi: 10.1186/s12984-025-01601-3.
8
[How valuable are genetic studies in paediatric neurology?].[基因研究在儿科神经病学中有多大价值?]
Rev Neurol. 2008;47 Suppl 1:S65-73.
9
The utility of the physical examination and investigations in the pediatricneurology consultation.体格检查和检查在儿科神经科会诊中的作用。
Pediatr Neurol. 2003 Feb;28(2):96-9. doi: 10.1016/s0887-8994(02)00494-0.
10
Pattern of neurological disorder presenting at a paediatric neurology clinic in Nigeria.尼日利亚一家儿科神经科诊所出现的神经障碍模式。
Ann Afr Med. 2007 Jun;6(2):73-5. doi: 10.4103/1596-3519.55712.

引用本文的文献

1
SLEEP-WAKE: A Comprehensive Mnemonic for Systematic Screening of Sleep-Related Issues.睡眠-觉醒:用于系统筛查睡眠相关问题的综合记忆法。
Pediatr Discov. 2025 Jun 14;3(2):e70010. doi: 10.1002/pdi3.70010. eCollection 2025 Jun.
2
Long-term, age-associated activity quantification in the DE50-MD dog model of Duchenne muscular dystrophy.在杜兴氏肌营养不良症的DE50-MD犬模型中进行长期的、与年龄相关的活动量化分析。
Dis Model Mech. 2025 Jul 1;18(7). doi: 10.1242/dmm.052135. Epub 2025 Jul 14.

本文引用的文献

1
Evidentiary basis of the first regulatory qualification of a digital primary efficacy endpoint.首个数字化主要疗效终点监管资格的证据基础。
Sci Rep. 2024 Nov 29;14(1):29681. doi: 10.1038/s41598-024-80177-9.
2
Lessons from a negative gene therapy trial for Duchenne muscular dystrophy.杜氏肌营养不良症阴性基因治疗试验的经验教训。
Nat Med. 2025 Jan;31(1):37-38. doi: 10.1038/s41591-024-03316-9.
3
Ethics of Wearable-Based Out-of-Hospital Cardiac Arrest Detection.可穿戴式院外心脏骤停检测的伦理学。
Circ Arrhythm Electrophysiol. 2024 Sep;17(9):e012913. doi: 10.1161/CIRCEP.124.012913. Epub 2024 Aug 22.
4
24-h continuous non-invasive multiparameter home monitoring of vitals in patients with Rett syndrome by an innovative wearable technology: evidence of an overlooked chronic fatigue status.采用创新可穿戴技术对雷特综合征患者进行24小时连续无创多参数生命体征家庭监测:慢性疲劳状态被忽视的证据
Front Neurol. 2024 Jun 17;15:1388506. doi: 10.3389/fneur.2024.1388506. eCollection 2024.
5
Validation of artificial intelligence for epileptic seizure detection: Moving from research into the clinic.用于癫痫发作检测的人工智能验证:从研究走向临床。
Dev Med Child Neurol. 2024 Sep;66(9):1114. doi: 10.1111/dmcn.16002. Epub 2024 Jun 19.
6
Objective measurement of movement variability using wearable sensors predicts ASD outcomes in infants at high likelihood for ASD and ADHD.使用可穿戴传感器对运动变异性进行客观测量可预测极有可能患自闭症谱系障碍(ASD)和注意力缺陷多动障碍(ADHD)的婴儿的ASD预后情况。
Autism Res. 2024 Jun;17(6):1094-1105. doi: 10.1002/aur.3150. Epub 2024 May 15.
7
Advancements in Wearable Digital Health Technology: A Review of Epilepsy Management.可穿戴数字健康技术的进展:癫痫管理综述
Cureus. 2024 Mar 27;16(3):e57037. doi: 10.7759/cureus.57037. eCollection 2024 Mar.
8
Stride Velocity 95th Centile Detects Decline in Ambulatory Function Over Shorter Intervals than the 6-Minute Walk Test or North Star Ambulatory Assessment in Duchenne Muscular Dystrophy.步速第95百分位数比6分钟步行试验或北极星动态评估能在更短时间间隔内检测出杜氏肌营养不良患者的动态功能下降。
J Neuromuscul Dis. 2024;11(3):701-714. doi: 10.3233/JND-230188.
9
Global, regional, and national burden of disorders affecting the nervous system, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.全球、区域和国家神经障碍疾病负担,1990-2021 年:2021 年全球疾病负担研究的系统分析。
Lancet Neurol. 2024 Apr;23(4):344-381. doi: 10.1016/S1474-4422(24)00038-3. Epub 2024 Mar 14.
10
Ethical considerations for integrating multimodal computer perception and neurotechnology.整合多模态计算机感知与神经技术的伦理考量
Front Hum Neurosci. 2024 Feb 16;18:1332451. doi: 10.3389/fnhum.2024.1332451. eCollection 2024.