Fisher C, Ramsay A D, Griffiths M, McDougall J
J Clin Pathol. 1985 Apr;38(4):403-8. doi: 10.1136/jcp.38.4.403.
The contribution of electron microscopy to the diagnosis of tumours in a general hospital has been investigated. During a three year period 235 cases were examined, of which 66 (28%) were diagnostic problems by light microscopy. In 42 (64%) of the problem cases a contribution towards diagnosis was made by ultrastructural examination, which was most useful for anaplastic polygonal cell tumours, of some value for spindle cell neoplasms, and least helpful in the further categorisation of metastatic carcinoma.
对一家综合医院中电子显微镜检查在肿瘤诊断方面的作用进行了研究。在三年期间共检查了235例病例,其中66例(28%)通过光学显微镜检查存在诊断难题。在42例(64%)疑难病例中,超微结构检查对诊断有帮助,这对间变性多角形细胞瘤最有用,对梭形细胞瘤有一定价值,而对转移性癌的进一步分类帮助最小。