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机械血栓切除术和导管直接溶栓在深静脉血栓形成患者中的应用:一家三级医院数据库分析

Mechanical thrombectomy and catheter directed thrombolysis utilization in patients with deep vein thrombosis: Analysis of a database of a tertiary hospital.

作者信息

Kuperin Alexandr, Seliverstov Evgeny, An Evgeny, Lebedev Igor, Zolotukhin Igor

机构信息

Department of Fundamental and Applied Research in Vascular Surgery, Pirogov Russian National Research Medical University, Moscow, Russia; Pirogov City Clinical Hospital No. 1, Moscow, Russia.

Department of Fundamental and Applied Research in Vascular Surgery, Pirogov Russian National Research Medical University, Moscow, Russia; Pirogov City Clinical Hospital No. 1, Moscow, Russia.

出版信息

J Vasc Surg Venous Lymphat Disord. 2025 May;13(3):102200. doi: 10.1016/j.jvsv.2025.102200. Epub 2025 Jan 29.

Abstract

OBJECTIVES

The aim of the study was to assess the mechanical thrombectomy (MT) and catheter-directed thrombolysis (CDT) use in patients with deep vein thrombosis (DVT) in tertiary care.

METHODS

We conducted a single-center retrospective cohort study. A tertiary hospital database from January 2022 to December 2023 was analyzed. All records of patients referred for DVT were extracted. The collected data included general patient information, medical history, results of physical examination, duplex ultrasound, and laboratory analyses. We assessed indications and contraindications for MT and CDT considering possible benefits and risks. We have identified patients who could be eligible for this technique.

RESULTS

A total of 2427 patients with DVT were referred to hospital from January 2022 to December 2023. Among them, 961 patients (39.6%) had no indications for hospital admission or refused it and were recommended to receive anticoagulation on an outpatient basis, and 1466 patients (60.4%) were admitted to the hospital. Among the hospitalized patients, 1277 had a proximal DVT and 189 had a distal DVT. The number of patients with iliofemoral DVT was 451 (18.6%). We found only 82 cases (3.4%) that could be potentially eligible for endovascular thrombectomy considering all possible indications and contraindications. Two attempts and 14 successful procedures were conducted during the period of the study.

CONCLUSIONS

The number of patients with DVT who could be eligible for MT and CDT in a tertiary hospital is low.

摘要

目的

本研究旨在评估三级医疗机构中深静脉血栓形成(DVT)患者机械血栓切除术(MT)和导管定向溶栓术(CDT)的应用情况。

方法

我们开展了一项单中心回顾性队列研究。分析了一家三级医院2022年1月至2023年12月的数据库。提取了所有因DVT转诊患者的记录。收集的数据包括患者一般信息、病史、体格检查结果、双功超声和实验室分析结果。我们在考虑潜在益处和风险的情况下评估了MT和CDT的适应证和禁忌证。我们确定了可能适合该技术的患者。

结果

2022年1月至2023年12月期间,共有2427例DVT患者转诊至该医院。其中,961例患者(39.6%)无住院指征或拒绝住院,建议门诊接受抗凝治疗,1466例患者(60.4%)住院。在住院患者中,1277例为近端DVT,189例为远端DVT。髂股静脉DVT患者有451例(18.6%)。考虑到所有可能的适应证和禁忌证,我们仅发现82例(3.4%)患者可能适合血管内血栓切除术。在研究期间进行了2次尝试,14例手术成功。

结论

在三级医院中,适合MT和CDT的DVT患者数量较少。

相似文献

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Underutilization of Thrombolytic Therapy for Patients Diagnosed with Acute Deep Venous Thrombosis in the Outpatient Setting.
Ann Vasc Surg. 2018 May;49:255-260. doi: 10.1016/j.avsg.2018.02.005. Epub 2018 Feb 28.

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Epidemiology and prevention of venous thromboembolism.静脉血栓栓塞症的流行病学和预防。
Nat Rev Cardiol. 2023 Apr;20(4):248-262. doi: 10.1038/s41569-022-00787-6. Epub 2022 Oct 18.

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