Petrosian Derek, Fadul Camilo E, Reilley Matthew, Dillon Patrick
Department of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Department of Neurology, University of Virginia, Charlottesville, Virginia, USA.
BMJ Case Rep. 2025 Jan 31;18(1):e263641. doi: 10.1136/bcr-2024-263641.
Brain metastases are rare and poorly understood complications of oesophageal carcinoma. This report describes a case of brain metastasis as the initial presentation of oesophageal adenocarcinoma. The rarity and the lack of prospective clinical trials of brain metastasis in oesophageal cancer result in the absence of treatment guidelines. Common treatments for brain metastases, regardless of tumour of origin, are applicable to oesophageal brain metastases and include surgical resection, whole brain radiation therapy, stereotactic radiosurgery, chemotherapy/immunotherapy and/or symptomatic control with steroids and anticonvulsants.
脑转移是食管癌罕见且了解甚少的并发症。本报告描述了一例以脑转移为首发表现的食管腺癌病例。食管癌脑转移的罕见性以及缺乏前瞻性临床试验，导致目前尚无治疗指南。无论原发肿瘤如何，脑转移的常见治疗方法都适用于食管癌脑转移，包括手术切除、全脑放射治疗、立体定向放射外科治疗、化疗/免疫治疗和/或使用类固醇及抗惊厥药进行症状控制。
