Pain Interference and Intensity in Relation to Abstinence Outcomes Following a One-Session Personalized Feedback Smoking Cessation Digital-Intervention.

Pain is a highly common and costly health problem that is strongly linked to cigarette smoking. Pain interference, the degree to which pain impedes physical, occupational, recreational, and social functioning, may have an important role in terms of smoking cessation. However, no study has examined the role of pain interference as a predictor of relapse following a quit attempt in a smoking cessation trial. The current study examined the role of pain interference, above the effects of pain intensity, on relapse following a quit attempt. Participants were 121 treatment-seeking adult cigarette smokers (29% female; Mage = 29.32, SD = 7.52) who attended a randomized-controlled trial (RCT) testing the effect of a digital single-session personalized feedback intervention (PFI) for distress tolerance and cigarette smoking behavior. Multiple logistic regressions were conducted to examine pain intensity and pain interference scores as predictors of 7-day point prevalence abstinence (PPA) at 2 weeks and 4 weeks following the 1-session intervention. Models controlled for sex, baseline cigarette dependence, treatment condition, and baseline distress tolerance. Pain interference was associated with higher odds of reporting relapse at 4-week post intervention (OR: 1.54, 95% CI [1.06, 2.25]).), while pain intensity only showed a non-significant association with higher odds of reporting relapse at 2-week (OR: 1.40, 95% CI [0.67, 2.94]). Conclusions: This prospective study highlights the effect of pain interference on later-stage relapse outcomes following participation in a cigarette smoking cessation program.