Wheldon Christopher W, Shahsavar Yeganeh, Choudhury Avishek, McCormick Bryan P, Albertorio-Díaz Juan R
Department of Social & Behavioral Sciences, College of Public Health, Temple University, 1301 Cecil B. Moore Ave. Ritter Hall Annex 9th Floor, Room 955, Philadelphia, PA, 19122, USA.
Cancer Control and Prevention Fox Chase Cancer Center Temple University, Philadelphia, PA, USA.
Sci Rep. 2025 Jan 31;15(1):3914. doi: 10.1038/s41598-025-85126-8.
Loneliness is recognized as a significant public health concern, affecting quality of life and health outcomes, including cancer-related outcomes. Thus, it is essential to understand the prevalence and risk factors for loneliness in people with cancer. Through an exploratory analysis of secondary data from the Health Information National Trends Survey, we investigated the prevalence and correlates of loneliness among adult cancer survivors (N = 1,234). An estimated 35.9% of participants experienced moderate to severe loneliness. In a series of multiple logistic regression models, we identified differences in sociodemographic, cancer-related factors, non-cancer comorbidities, social isolation, social support, and social media use behaviors in the odds of reporting moderate-severe loneliness. In our fully adjusted model, years since cancer diagnosis, fair-poor overall health, moderate-high psychological distress, and having children living in the household were all positively and independently associated with moderate-severe loneliness. In this same model, being married and reporting some types of social support were negatively associated with moderate-severe loneliness. This study underscores the multifaceted nature of loneliness among cancer survivors, revealing a complex interplay of demographic, health-related, and social factors.
孤独被认为是一个重大的公共卫生问题，会影响生活质量和健康结果，包括与癌症相关的结果。因此，了解癌症患者中孤独的患病率和风险因素至关重要。通过对健康信息国家趋势调查的二手数据进行探索性分析，我们调查了成年癌症幸存者（N = 1234）中孤独的患病率及其相关因素。估计35.9%的参与者经历了中度至重度孤独。在一系列多元逻辑回归模型中，我们确定了在报告中度至重度孤独的几率方面，社会人口统计学、癌症相关因素、非癌症合并症、社会隔离、社会支持和社交媒体使用行为的差异。在我们的完全调整模型中，自癌症诊断以来的年数、总体健康状况一般至较差、中度至高度心理困扰以及家中有孩子生活，均与中度至重度孤独呈正相关且独立相关。在同一模型中，已婚和报告某些类型的社会支持与中度至重度孤独呈负相关。这项研究强调了癌症幸存者中孤独的多面性，揭示了人口统计学、健康相关和社会因素之间复杂的相互作用。
