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在非传统的非体外循环冠状动脉搭桥中心建立非机器人微创直接冠状动脉搭桥术的经验。

Experience in setting up non-robotic minimally invasive direct coronary artery bypass grafting in a non-routine off-pump coronary artery bypass center.

作者信息

Sugimura Yukiharu, Suzuki Tomoyuki, Bauer Sebastian Johannes, Schoettler Friederike Irmgard, Immohr Moritz Benjamin, Maliwa Michael André, Mehdiani Arash, Tewarie Lachmandath, Schaelte Gereon, Moza Ajay, Akhyari Payam

机构信息

Department of Thoracic and Cardiovascular Surgery, West-German Heart and Vascular Center Essen, University Duisburg-Essen, Essen, Germany.

Department of Cardiac Surgery, Medical Faculty and RWTH University Hospital Aachen, RWTH Aachen University, Aachen, Germany.

出版信息

Eur J Med Res. 2025 Jan 31;30(1):64. doi: 10.1186/s40001-025-02320-0.

DOI:10.1186/s40001-025-02320-0
PMID:39891213
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11783730/
Abstract

BACKGROUND

The safety of minimally invasive direct coronary artery bypass (MIDCAB) has been proven. Nevertheless, reports on clinical outcomes in MIDCAB and the learning curve of this challenging technique in a non-routine off-pump coronary artery bypass (OPCAB) center are still limited. Here, we introduce our clinical outcomes of non-robotic MIDCAB.

METHODS

Between August 2022 and March 2024, 72 consecutive patients with a mean age of 67.4 ± 9.5 years underwent non-robotic MIDCAB (defined as off-pump bypass grafting of the left internal mammary artery to the left anterior descending artery through left-sided mini-thoracotomy). We analyzed operation time and incidence of major adverse cardiac and cerebrovascular events (MACCE). Further, subgroup analyses included body mass index (BMI) with a cut-off of 30 kg/m [BMI ≧ 30: n = 18 (25.0%)] and body surface area (BSA) with a cut-off of 2.0 m [BSA ≧ 2.0: n = 34 (47.2%)].

RESULTS

All patients survived, whereas MACCE occurred in 4 patients (5.6%). By correlation analyses, no learning curve for operation time was observed in all cases analysis (p = 0.79), but MACCE (n = 4, 5.6%) exclusively observed in the first 34 patients. Furthermore, BMI ≧ 30 or BSA ≧ 2.0 was not significantly related to longer operation time (p = 0.42 and p = 0.52, respectively) and MACCE (p = 0.26 and p = 0.35, respectively). In addition, body size had no effect on operation time according to multiple regression analysis (p = 0.36).

CONCLUSIONS

Our study suggested that implementing non-robotic MIDCAB can be safely accomplished at a center with no previous routine in OPCAB surgery, even for patients with bigger body sizes. MACCE occurs more frequently in the early stages when adopting this surgical technique.

摘要

背景

微创直接冠状动脉旁路移植术(MIDCAB)的安全性已得到证实。然而,关于MIDCAB临床结果以及在非常规非体外循环冠状动脉旁路移植术(OPCAB)中心开展这项具有挑战性技术的学习曲线的报道仍然有限。在此,我们介绍非机器人辅助MIDCAB的临床结果。

方法

2022年8月至2024年3月期间,72例平均年龄为67.4±9.5岁的连续患者接受了非机器人辅助MIDCAB(定义为通过左侧小切口将左乳内动脉非体外循环旁路移植至左前降支)。我们分析了手术时间以及主要不良心脑血管事件(MACCE)的发生率。此外,亚组分析包括体重指数(BMI)以30kg/m为界值(BMI≥30:n = 18例,占25.0%)和体表面积(BSA)以2.0m²为界值(BSA≥2.0:n = 34例,占47.2%)。

结果

所有患者均存活,而4例患者(5.6%)发生了MACCE。通过相关性分析,在所有病例分析中未观察到手术时间的学习曲线(p = 0.79),但MACCE(n = 4例,5.6%)仅在前34例患者中观察到。此外,BMI≥30或BSA≥2.0与更长的手术时间(分别为p = 0.42和p = 0.52)以及MACCE(分别为p = 0.26和p = 0.35)均无显著相关性。另外,根据多元回归分析,体型对手术时间无影响(p = 0.36)。

结论

我们的研究表明,即使对于体型较大的患者,在以前没有OPCAB手术常规经验的中心也可以安全地开展非机器人辅助MIDCAB。采用这种手术技术时,MACCE在早期阶段更频繁发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13b0/11783730/e0e1925dc515/40001_2025_2320_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13b0/11783730/d334f9448dda/40001_2025_2320_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13b0/11783730/1f9b8673b629/40001_2025_2320_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13b0/11783730/e0e1925dc515/40001_2025_2320_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13b0/11783730/d334f9448dda/40001_2025_2320_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13b0/11783730/1f9b8673b629/40001_2025_2320_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13b0/11783730/e0e1925dc515/40001_2025_2320_Fig3_HTML.jpg

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