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不同领域水凝胶研究的文献计量分析:水凝胶应用的趋势与演变

A bibliometric analysis of hydrogel research in various fields: the trends and evolution of hydrogel application.

作者信息

Yuan Zhong-Zhu, Fan Yu-Zhou, Cheng Shao-Jun, Wei Feng-Jie, Gao Jing, Wang Chen-Xi, Song Bo-Shuang, Tan Si-Lu, Gao Si-Lian, Kang Juan-Juan, Liu Yan, Li Sheng-Hong

机构信息

State Key Laboratory of Southwestern Chinese Medicine Resources, and Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.

College of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.

出版信息

J Nanobiotechnology. 2025 Jan 31;23(1):70. doi: 10.1186/s12951-025-03090-x.

Abstract

Hydrogel, a polymer material with a three-dimensional structure, has considerably expanded in research across multiple fields lately. However, the lack of a comprehensive review integrating the research status of hydrogel across diverse fields has hindered the development of hydrogel. This bibliometric analysis reviewed the hydrogel-related research over the past decades, emphasizing the evolution, status, and future directions within a multitude of fields, such as materials science, chemistry, polymer science, engineering, physics, biochemistry molecular biology, pharmacology pharmacy, cell biology, biotechnology applied microbiology, etc. We encapsulated applications and the potential of hydrogel in wound healing, drug delivery, cell encapsulation, bioprinting, tissue engineering, electronic products, environment applications, and disease treatment. This study integrated the current matrix system and characteristics of hydrogels, aiming to offer a cross-field reference for hydrogel researchers and promote the advancement of hydrogel research. Furthermore, we proposed a novel and reproducible bibliometric research paradigm, which can provide a more comprehensive analysis of the trends and trajectory of a research field.

摘要

水凝胶是一种具有三维结构的高分子材料,近年来在多个领域的研究中得到了显著扩展。然而,缺乏对水凝胶在不同领域研究现状的综合综述阻碍了水凝胶的发展。这项文献计量分析回顾了过去几十年与水凝胶相关的研究,重点关注了材料科学、化学、高分子科学、工程学、物理学、生物化学与分子生物学、药理学与药剂学、细胞生物学、生物技术与应用微生物学等众多领域内的发展演变、现状及未来方向。我们总结了水凝胶在伤口愈合、药物递送、细胞封装、生物打印、组织工程、电子产品、环境应用及疾病治疗等方面的应用及潜力。本研究整合了当前水凝胶的基质系统和特性,旨在为水凝胶研究人员提供跨领域参考,并推动水凝胶研究的进展。此外,我们提出了一种新颖且可重复的文献计量研究范式,它能够对一个研究领域的趋势和轨迹进行更全面的分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e32d/11783735/5454dad7cf46/12951_2025_3090_Fig1_HTML.jpg

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