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紧急警报:伊朗存在通过输血传播登革热感染的潜在风险。

Urgent Alert: Potential Risk of Dengue Infection Transmission Through Blood Transfusion in Iran.

作者信息

Taghinejad Zahra, Asgharzadeh Mohammad, Pourfathollah Ali Akbar

机构信息

Department of Hematology and Blood Banking, Faculty of Basic Medical Sciences, Tarbiat Modares University, Tehran, Iran.

Biotechnology Research Center and Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Arch Iran Med. 2024 Dec 1;27(12):693-699. doi: 10.34172/aim.31756.

DOI:10.34172/aim.31756
PMID:39891457
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11786206/
Abstract

Dengue infection is an emerging public health issue in Iran, with about 149 confirmed newly infected cases. It can be transmitted by the bite of infected Aedes mosquitoes and even nosocomial routes. Due to the rapid replication and geographical spread of the mosquito, there is a potential risk of increased infected individuals. Given the possibility of the transmission of dengue infection through transfusion, it is important to implement policies to improve blood safety. Proper donor selection by utilizing appropriate blood donor questionnaires and performing general physical examinations, along with performing sensitive diagnostic tests on blood donor samples, utilizing pathogen reduction techniques, and implementing lookback programs, can be effective in reducing the risk of transfusion-transmitted dengue virus (TT-DENV).

摘要

登革热感染是伊朗一个新出现的公共卫生问题,新确诊的感染病例约有149例。它可通过受感染的伊蚊叮咬传播,甚至可通过医院感染途径传播。由于蚊子的快速繁殖和地理扩散,存在感染个体增加的潜在风险。鉴于登革热感染通过输血传播的可能性,实施改善血液安全的政策很重要。通过使用适当的献血者问卷进行适当的献血者选择、进行一般体格检查、对献血者样本进行敏感的诊断测试、利用病原体灭活技术以及实施追溯计划,可有效降低输血传播登革热病毒(TT-DENV)的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28a2/11786206/1170d4283751/aim-27-693-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28a2/11786206/5501601dc1c3/aim-27-693-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28a2/11786206/7a629b402edd/aim-27-693-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28a2/11786206/1170d4283751/aim-27-693-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28a2/11786206/5501601dc1c3/aim-27-693-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28a2/11786206/7a629b402edd/aim-27-693-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28a2/11786206/1170d4283751/aim-27-693-g003.jpg

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本文引用的文献

1
Dengue virus transmission risk in blood donation: Evidence from Thailand.献血传播登革病毒的风险:来自泰国的证据。
J Med Virol. 2024 Jun;96(6):e29689. doi: 10.1002/jmv.29689.
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Medically Significant Vector-Borne Viral Diseases in Iran.伊朗具有医学重要性的媒介传播病毒性疾病。
Microorganisms. 2023 Dec 18;11(12):3006. doi: 10.3390/microorganisms11123006.
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Mechanical transmission of dengue virus by Aedes aegypti may influence disease transmission dynamics during outbreaks.埃及伊蚊对登革热病毒的机械传播可能会影响疫情爆发期间疾病的传播动态。
EBioMedicine. 2023 Aug;94:104723. doi: 10.1016/j.ebiom.2023.104723. Epub 2023 Jul 22.
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Rapid Diagnostic Tests for the Detection of the Four Dengue Virus Serotypes in Clinically Relevant Matrices.用于在临床相关基质中检测四种登革热病毒血清型的快速诊断检测。
Microbiol Spectr. 2023 Feb 14;11(1):e0279622. doi: 10.1128/spectrum.02796-22. Epub 2023 Jan 23.
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Management of Dengue: An Updated Review.登革热管理:最新综述。
Indian J Pediatr. 2023 Feb;90(2):168-177. doi: 10.1007/s12098-022-04394-8. Epub 2022 Dec 27.
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Innate and adaptive immune evasion by dengue virus.登革热病毒的先天和适应性免疫逃逸。
Front Cell Infect Microbiol. 2022 Sep 16;12:1004608. doi: 10.3389/fcimb.2022.1004608. eCollection 2022.
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A risk assessment model for transfusion transmission of dengue.登革热输血传播风险评估模型。
Lett Appl Microbiol. 2022 Nov;75(5):1330-1335. doi: 10.1111/lam.13802. Epub 2022 Aug 18.
8
Dengue infection: Global importance, immunopathology and management.登革热感染:全球重要性、免疫病理学和管理。
Clin Med (Lond). 2022 Jan;22(1):9-13. doi: 10.7861/clinmed.2021-0791.
9
Dengue hemorrhagic fever and the liver.登革出血热与肝脏
World J Hepatol. 2021 Dec 27;13(12):1968-1976. doi: 10.4254/wjh.v13.i12.1968.
10
Production, Transmission, Pathogenesis, and Control of Dengue Virus: A Literature-Based Undivided Perspective.登革热病毒的产生、传播、发病机制与控制:基于文献的整体视角。
Biomed Res Int. 2021 Dec 15;2021:4224816. doi: 10.1155/2021/4224816. eCollection 2021.