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化疗引起脱发患者的红光疗法。

Red light therapy for patients with chemotherapy-induced alopecia.

作者信息

Rose Lucy, Mager Layna, Hordinsky Maria, Dulmage Brittany

机构信息

The Ohio State University College of Medicine, Columbus, OH, USA.

Department of Dermatology, The University of Minnesota Medical School, Minneapolis, MN, USA.

出版信息

Support Care Cancer. 2025 Feb 1;33(2):137. doi: 10.1007/s00520-025-09209-y.

DOI:10.1007/s00520-025-09209-y
PMID:39891783
Abstract

We have taken great interest in the topic of red light therapy (RLT) for the treatment of hair loss secondary to cancer therapies. On April 7, 2024, we searched through two private Facebook groups (Fig. 1) intended for patients who used scalp cooling for prevention of chemotherapy-induced hair loss. In these groups, we found several posts inquiring about the use of RLT (Fig. 2). Posts ranged from patients asking if others in the group have used RLT, if RLT is safe to use while scalp cooling, and recommendations for how long to wait to initiate RLT after chemotherapy infusions are completed. Despite the rise in popularity of RLT for the management of hair loss, to date, only two clinical trials have included patients with cancer treatment-induced hair loss, which showed higher hair counts and increased quality of life in those who used RLT [1, 2]. Furthermore, no formal recommendations from oncologists or scalp cooling companies have been made to help guide patients when considering using RLT.

摘要

我们对红光疗法(RLT)治疗癌症治疗引起的脱发这一主题非常感兴趣。2024年4月7日,我们在两个面向使用头皮冷却预防化疗引起脱发的患者的私人Facebook群组中进行了搜索(图1)。在这些群组中,我们发现了几篇询问RLT使用情况的帖子(图2)。帖子内容包括患者询问群组中的其他人是否使用过RLT、在进行头皮冷却时使用RLT是否安全,以及关于化疗输液完成后等待多久开始使用RLT的建议。尽管RLT在脱发管理中的应用越来越普遍,但迄今为止,只有两项临床试验纳入了癌症治疗引起脱发的患者,结果显示使用RLT的患者头发数量增加,生活质量提高[1,2]。此外,肿瘤学家或头皮冷却公司尚未给出正式建议,以帮助指导患者在考虑使用RLT时做出决策。

相似文献

1
Red light therapy for patients with chemotherapy-induced alopecia.化疗引起脱发患者的红光疗法。
Support Care Cancer. 2025 Feb 1;33(2):137. doi: 10.1007/s00520-025-09209-y.
2
Characterization of the role of Facebook groups for patients who use scalp cooling therapy: a survey study.头皮冷却疗法使用者的 Facebook 群组角色特征:一项调查研究。
Support Care Cancer. 2024 May 15;32(6):351. doi: 10.1007/s00520-024-08534-y.
3
Effect of a Scalp Cooling Device on Alopecia in Women Undergoing Chemotherapy for Breast Cancer: The SCALP Randomized Clinical Trial.头皮冷却装置对乳腺癌化疗女性脱发的影响:SCALP 随机临床试验。
JAMA. 2017 Feb 14;317(6):596-605. doi: 10.1001/jama.2016.20939.
4
A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention.《理解化疗引起的脱发及其预防的临床和生物学指南》
Oncologist. 2018 Jan;23(1):84-96. doi: 10.1634/theoncologist.2017-0263. Epub 2017 Sep 26.
5
The use of scalp cooling for chemotherapy-induced hair loss.头皮冷却用于化疗引起的脱发。
Br J Nurs. 2016;25(10):S22, S24-7. doi: 10.12968/bjon.2016.25.10.S22.
6
Treatment of chemotherapy-induced alopecia.化疗引起的脱发的治疗。
Dermatol Ther. 2011 Jul-Aug;24(4):432-42. doi: 10.1111/j.1529-8019.2011.01430.x.
7
The DigniCap Scalp Cooling System and its use in the treatment of chemotherapy-induced alopecia.DigniCap 头皮冷却系统及其在化疗引起的脱发治疗中的应用。
Future Oncol. 2018 Oct;14(24):2461-2469. doi: 10.2217/fon-2018-0178. Epub 2018 Jul 12.
8
Scalp Cooling: The Prevention of Chemotherapy-Induced Alopecia
.头皮冷却:预防化疗引起的脱发
Clin J Oncol Nurs. 2017 Aug 1;21(4):413-415. doi: 10.1188/17.CJON.413-415.
9
Scalp cooling for hair loss prevention in female Japanese breast cancer patients receiving (neo)adjuvant chemotherapy.头皮冷却预防接受(新)辅助化疗的日本女性乳腺癌患者脱发。
Support Care Cancer. 2021 Jan;29(1):437-443. doi: 10.1007/s00520-020-05506-w. Epub 2020 May 9.
10
Association Between Use of a Scalp Cooling Device and Alopecia After Chemotherapy for Breast Cancer.头皮冷却装置的使用与乳腺癌化疗后脱发之间的关联。
JAMA. 2017 Feb 14;317(6):606-614. doi: 10.1001/jama.2016.21038.

本文引用的文献

1
The effect of a helmet type, home-use low-level light therapy device for chemotherapy-induced alopecia: study protocol for a randomized controlled trial.头盔类型、家用低水平光疗设备对化疗引起的脱发的影响:一项随机对照试验的研究方案。
Trials. 2023 Dec 5;24(1):789. doi: 10.1186/s13063-023-07823-x.
2
Effect of Skin Type on Efficacy of Laser Treatment for Androgenetic Alopecia: A Review of the Literature.皮肤类型对雄激素性脱发激光治疗效果的影响:文献综述
Skin Appendage Disord. 2023 Oct;9(5):317-324. doi: 10.1159/000528518. Epub 2023 Jul 3.
3
Retrospective review of oral and topical minoxidil for cancer treatment-induced hair loss.
口服和外用米诺地尔治疗癌症导致脱发的回顾性研究。
Arch Dermatol Res. 2023 Nov;315(9):2613-2615. doi: 10.1007/s00403-023-02660-z. Epub 2023 Jul 8.
4
The use of photobiomodulation therapy for the management of chemotherapy-induced alopecia: a randomized, controlled trial (HAIRLASER trial).应用强脉冲光疗法治疗化疗所致脱发的随机对照试验(HAIRLASER 试验)。
Support Care Cancer. 2023 Apr 15;31(5):269. doi: 10.1007/s00520-023-07743-1.
5
Role of Low-Level Light Therapy (LLLT) in Androgenetic Alopecia.低强度光疗(LLLT)在雄激素性脱发中的作用。
J Cutan Aesthet Surg. 2021 Oct-Dec;14(4):385-391. doi: 10.4103/JCAS.JCAS_218_20.
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Results of low-level laser therapy in the treatment of hair growth: An Egyptian experience.低水平激光疗法治疗毛发生长的疗效:埃及的经验。
Dermatol Ther. 2021 May;34(3):e14940. doi: 10.1111/dth.14940. Epub 2021 Apr 17.
7
Comparative effectiveness of low-level laser therapy for adult androgenic alopecia: a system review and meta-analysis of randomized controlled trials.低水平激光疗法治疗成人雄激素性脱发的疗效比较:系统评价和随机对照试验的荟萃分析。
Lasers Med Sci. 2019 Aug;34(6):1063-1069. doi: 10.1007/s10103-019-02723-6. Epub 2019 Jan 31.
8
The effectiveness of adding low-level light therapy to minoxidil 5% solution in the treatment of patients with androgenetic alopecia.在雄激素性脱发患者治疗中,将低能量光疗添加至5%米诺地尔溶液的有效性。
Indian J Dermatol Venereol Leprol. 2018 Sep-Oct;84(5):547-553. doi: 10.4103/ijdvl.IJDVL_1156_16.