Edo Great Iruoghene, Ndudi Winifred, Ali Ali B M, Yousif Emad, Zainulabdeen Khalid, Akpoghelie Patrick Othuke, Isoje Endurance Fegor, Igbuku Ufuoma Augustina, Opiti Rapheal Ajiri, Athan Essaghah Arthur Efeoghene, Ahmed Dina S, Umar Huzaifa, Alamiery Ahmed A
Department of Chemistry, Faculty of Science, Delta State University of Science and Technology, Ozoro, Delta State, Nigeria; Department of Chemistry, College of Sciences, Al-Nahrain University, Baghdad, Iraq.
Department of Chemistry, Faculty of Science, Delta State University of Science and Technology, Ozoro, Delta State, Nigeria.
Carbohydr Res. 2025 Apr;550:109409. doi: 10.1016/j.carres.2025.109409. Epub 2025 Jan 31.
The properties and potential applications of chitosan have attracted a lot of interest; each year, the number of publications and patents based on this polymer increases. A significant obstacle to the application of chitosan is its limited solubility in basic and neutral solutions. The fact that chitosan is a series of molecules with variations in size, content, and monomer distribution rather than a single polymer with a well-defined structure and a natural origin is another significant barrier. Some of the claimed biological qualities are distinct, and these characteristics have a fundamental effect on the polymer's technological and biological performance. The poor solubility of the polymer can be improved by chitosan chemistry, and in this assessment, we discuss the changes made to make chitosan more soluble and its possible uses. We concentrate on a few of the primary biological characteristics of chitosan and how they relate to the physicochemical characteristics of the polymer. The use of chitosan in the environmentally friendly manufacture of metallic nanoparticles as well as its usage as a booster for biocatalysts are two further applications of polymers that are linked to green processes that we revisit. This study also presents information about utilizing chitosan's technological advantages.
壳聚糖的特性和潜在应用引起了广泛关注;每年,基于这种聚合物的出版物和专利数量都在增加。壳聚糖应用的一个重大障碍是其在碱性和中性溶液中的溶解度有限。壳聚糖是一系列大小、含量和单体分布各异的分子,而非具有明确结构和天然来源的单一聚合物,这也是一个重大障碍。一些声称的生物学特性各不相同,这些特性对聚合物的技术和生物学性能具有根本性影响。聚合物的低溶解度可通过壳聚糖化学方法加以改善,在本评估中,我们将讨论为提高壳聚糖溶解度所做的改变及其可能的用途。我们重点关注壳聚糖的一些主要生物学特性以及它们与聚合物物理化学特性的关系。壳聚糖在金属纳米颗粒的环保制造中的应用以及作为生物催化剂促进剂的用途,是我们重新审视的与绿色工艺相关的聚合物的另外两个应用。本研究还介绍了利用壳聚糖技术优势的相关信息。