Kato Ken, Di Vece Davide, Kitagawa Mari, Yamamoto Kayo, Miyakoda Ko, Aoki Shuhei, Goto Hiroki, Kitahara Hideki, Kobayashi Yoshio, Templin Christian
Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
Internal Medicine B, University Medicine Greifswald, Greifswald, Germany; First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, Genoa, Italy.
J Cardiol. 2025 Apr;85(4):263-267. doi: 10.1016/j.jjcc.2025.01.009. Epub 2025 Jan 30.
Takotsubo syndrome (TTS) is a complex cardiovascular condition characterized by transient left and/or right ventricular dysfunction in the absence of a coronary artery culprit lesion. The InterTAK registry, a large international collaborative registry, has significantly advanced our understanding of TTS. This review summarizes key findings from the InterTAK registry, including epidemiology, clinical presentation, comorbidities, outcomes, and treatment. The registry has revealed the diverse clinical spectrum of TTS, including atypical presentations, and identified various risk factors associated with adverse outcomes. The InterTAK registry has been instrumental in shaping the current understanding of TTS and will continue to guide future research and clinical practice.
应激性心肌病（TTS）是一种复杂的心血管疾病，其特征是在没有冠状动脉罪犯病变的情况下出现短暂的左心室和/或右心室功能障碍。国际应激性心肌病注册研究（InterTAK）是一个大型国际合作注册研究，极大地增进了我们对TTS的了解。本综述总结了InterTAK注册研究的主要发现，包括流行病学、临床表现、合并症、预后和治疗。该注册研究揭示了TTS多样的临床谱，包括非典型表现，并确定了与不良预后相关的各种危险因素。InterTAK注册研究在形成当前对TTS的认识方面发挥了重要作用，并将继续指导未来的研究和临床实践。
