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自身免疫性骨髓纤维化合并2型糖尿病患者发生坏死性筋膜炎:1例罕见病例报告

Causing Necrotizing Fasciitis in a Patient of Autoimmune Myelofibrosis and Type 2 Diabetes: A Rare Case Report.

作者信息

Kumar Rahul, Kakar Atul, Batra Tanvi, Shujanya Prateek, Chauhan Akashdeep

机构信息

DNB Trainee, Department of Internal Medicine, Sir Ganga Ram Hospital, New Delhi, India, Corresponding Author.

DNB, MBBS, Chairman and Senior Consultant, Department of Internal Medicine, Sir Ganga Ram Hospital, New Delhi, India.

出版信息

J Assoc Physicians India. 2025 Jan;73(1):87-89. doi: 10.59556/japi.73.0777.

Abstract

Demodicosis is a skin disease caused by the Demodex mite. It commonly involves areas in or near pilosebaceous units. Infestation with Demodex is asymptomatic but may have a pathogenic role in immunocompromised individuals or when present in high densities. We hereby report a case of a 36-year-old fruit seller, a known case of diabetes, rheumatic heart disease, and autoimmune myelofibrosis, who presented with progressive right periorbital swelling with blackish discoloration, purulent discharge, and fever. Incision and debridement were performed repeatedly, and tissue was sent for microbiology, which revealed Demodex folliculorum. The patient was treated with IV antibiotics, IV amphotericin B empirically, and oral ivermectin for Demodex.

摘要

蠕形螨病是一种由蠕形螨引起的皮肤病。它通常累及毛囊皮脂腺单位内或其附近的区域。感染蠕形螨通常无症状,但在免疫功能低下的个体中或高密度存在时可能具有致病作用。我们在此报告一例36岁的水果商贩,他患有糖尿病、风湿性心脏病和自身免疫性骨髓纤维化,出现了右侧眶周进行性肿胀、皮肤发黑、脓性分泌物和发热症状。反复进行了切开清创术,并将组织送去做微生物学检查,结果发现了毛囊蠕形螨。患者接受了静脉注射抗生素、经验性静脉注射两性霉素B以及口服伊维菌素治疗蠕形螨感染。

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