2 型糖尿病与感染：秘鲁患者的横断面研究。
Type 2 Diabetes Mellitus and Infestation: A Cross-Sectional Study in Peruvian Patients.
机构信息
Escuela de Medicina, Universidad César Vallejo, Trujillo 13001, Peru.
Hospital de Apoyo de Palpa, Ica 11330, Peru.
出版信息
Int J Environ Res Public Health. 2022 Oct 20;19(20):13582. doi: 10.3390/ijerph192013582.
BACKGROUND
is a mite that causes human demodicosis, which is characterized by producing lesions on the face, and its infestation could be associated with factors that alter the immune response, including Type 2 Diabetes (T2D). This study aimed to evaluate the relationship between T2D and infestation in patients attended at a hospital in Peru in 2021.
METHODS
A cross-sectional study enrolling patients who were classified according to the presence (n = 100) and absence (n = 100) of T2D was conducted. Information was obtained on age, sex, domestic animal husbandry, and symptoms and signs associated with demodicosis. Demodicosis was determined to be present when counts of greater than five mites per cm were found in superficial facial skin biopsies.
RESULTS
A frequency of demodicosis in 76 and 35 patients with and without T2D, respectively, was observed. In the multivariate analysis adjusted for confounders age, sex, and domestic animal husbandry, T2D was found to be associated with infestation (PR: 2.13; 95% CI95: 1.42-3.19).
CONCLUSIONS
T2D was associated with infestation. In this sense, it is important to strengthen surveillance to identify of infestation in people with T2D.
背景
蠕形螨是一种引起人类蠕形螨病的螨虫，其特征是在面部产生病变，其感染可能与改变免疫反应的因素有关，包括 2 型糖尿病（T2D）。本研究旨在评估 2021 年在秘鲁一家医院就诊的患者中 T2D 与蠕形螨感染之间的关系。
方法
进行了一项横断面研究，纳入了根据是否存在 T2D（n=100）和不存在 T2D（n=100）进行分类的患者。收集了年龄、性别、家庭畜牧业以及与蠕形螨病相关的症状和体征的信息。当在浅表面部皮肤活检中发现每平方厘米大于五螨虫时，即确定存在蠕形螨病。
结果
分别在有和没有 T2D 的 76 名和 35 名患者中观察到蠕形螨病的频率。在调整混杂因素（年龄、性别和家庭畜牧业）的多变量分析中，T2D 与蠕形螨感染有关（PR：2.13；95%CI95：1.42-3.19）。
结论
T2D 与蠕形螨感染有关。在这方面，加强对 T2D 患者蠕形螨感染的监测非常重要。
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