Lieberman Jay A, Abrams Elissa M, Katari Priya, Ben-Shoshan Moshe
Department of Pediatrics, Division of Pulmonology, Allergy & Immunology, University of Tennessee Health Science Center, LeBonheur Children's Hospital, Memphis, Tenn.
Section of Allergy and Clinical Immunology, Department of Pediatrics, University of Manitoba, Winnipeg, MB, Canada.
J Allergy Clin Immunol Pract. 2025 Apr;13(4):723-729. doi: 10.1016/j.jaip.2024.12.044. Epub 2025 Jan 31.
The management of food allergy has evolved over the past several years with regulatory approval of food allergy therapeutics as well as the common practice of oral immunotherapy. Whether a patient or family chooses one of these therapies or avoidance, they are still considered at risk of reaction, and thus clinicians still need to stay up to date with the latest advancements in the management of anaphylaxis in patients with food allergy. This review will highlight some of these updates, starting with the definition, diagnosis, and classifications of anaphylaxis. It will then review the latest updates in the management of food anaphylaxis in the community. Finally, the review will discuss the latest in epinephrine including recommendations on epinephrine dosing and novel routes of epinephrine administration.
在过去几年中,随着食物过敏疗法获得监管批准以及口服免疫疗法的普遍应用,食物过敏的管理方式不断演变。无论患者或其家属选择这些疗法中的一种还是采取回避措施,他们仍被视为有发生反应的风险,因此临床医生仍需要紧跟食物过敏患者过敏反应管理的最新进展。本综述将重点介绍其中的一些更新内容,首先是过敏反应的定义、诊断和分类。然后将回顾社区中食物过敏反应管理的最新进展。最后,本综述将讨论肾上腺素的最新情况,包括肾上腺素剂量的建议和肾上腺素给药的新途径。