阿尔茨海默病患者身体活动的相关因素：一项针对患者及其照料者的横断面研究
Factors Associated With Physical Activity in Alzheimer's Disease: A Cross-Sectional Study of Individuals and Their Caregivers.
作者信息
Clina Julianne G, Bodde Amy E, Chang Joy, Helsel Brian C, Sherman Joseph R, Vidoni Eric D, Williams Kristine N, Washburn Richard A, Donnelly Joseph E, Ptomey Lauren T
机构信息
Department of Internal Medicine, The University of Kansas Medical Center, Kansas City, KS, USA.
Department of Neurology, The University of Kansas Medical Center, Kansas City, KS, USA.
出版信息
J Aging Health. 2025 Feb 2:8982643251318766. doi: 10.1177/08982643251318766.
INTRODUCTION
Physical activity (PA) is associated with better outcomes in individuals living with Alzheimer's and related dementia (ADRD). We examined environmental, intra-, and interpersonal correlates of PA for persons living with ADRD.
METHODS
PA (accelerometry), cognitive function, physical function, and sociodemographic factors were collected in adults with ADRD and their caregivers. Spearman's correlations and generalized linear models were used to evaluate factors associated with PA of persons living with ADRD.
RESULTS
Valid data were obtained from 65 pairs of adults living with ADRD (73.6 ± 8.4 years, 39.4% female) and caregivers (69.4 ± 9.4 years, 69.2% female, 93.8% spouse). Moderate-to-vigorous PA (MVPA) and light PA of persons living with ADRD were correlated with upper and lower body strength, aerobic fitness, and agility. MVPA and sedentary time of persons living with ADRD were associated with that of their caregiver.
CONCLUSION
Physical function and caregiver PA may be targets for interventions in those living with ADRD.
引言
身体活动（PA）与阿尔茨海默病及相关痴呆症（ADRD）患者的更好预后相关。我们研究了ADRD患者PA的环境、个体内和人际相关因素。
方法
收集了ADRD成人患者及其照料者的PA（加速度计测量）、认知功能、身体功能和社会人口学因素。采用Spearman相关性分析和广义线性模型来评估与ADRD患者PA相关的因素。
结果
从65对ADRD成人患者（73.6±8.4岁，39.4%为女性）及其照料者（69.4±9.4岁，69.2%为女性，93.8%为配偶）中获得了有效数据。ADRD患者的中度至剧烈身体活动（MVPA）和轻度PA与上下肢力量、有氧适能和敏捷性相关。ADRD患者的MVPA和久坐时间与其照料者的相关。
结论
身体功能和照料者的PA可能是ADRD患者干预措施的目标。
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