Weiner S
J Exp Zool. 1985 Apr;234(1):7-15. doi: 10.1002/jez.1402340103.
The skeletal plates and teeth of the echinoid Paracentrotus lividus contain a heterogeneous assemblage of macromolecules that are not part of the connective tissue, but are presumably intimately associated with the mineral phase. Upon dissolution of the Mg-calcite mineral phase, some of these molecules are insoluble. The insoluble fractions of the teeth and skeletal plates are quite different, the former being predominantly protein and the latter, primarily some unknown nonproteinaceous material. The soluble constituents are similar in both tissues. These hydrophilic macromolecules have been partially separated and characterized. In both hard parts, two distinct classes of macromolecules are present, as indicated by the amino acid compositions of their protein constituents. These two classes of macromolecules are also present in the shells of a foraminifer and in various mollusks, both of which are formed by the "organic matrix-mediated" biomineralization process. The locations of these macromolecules in the teeth and skeletal plates are not known, nor whether they form coherent structures. It is therefore premature to conclude that these macromolecules do function as an organic matrix, although the results presented are in agreement with such an interpretation.
海胆Paracentrotus lividus的骨骼板和牙齿含有大分子的异质组合，这些大分子不是结缔组织的一部分，但可能与矿化相密切相关。在Mg-方解石矿化相溶解后，其中一些分子是不溶的。牙齿和骨骼板的不溶部分有很大不同，前者主要是蛋白质，后者主要是一些未知的非蛋白质物质。两种组织中的可溶成分相似。这些亲水性大分子已被部分分离和表征。在这两个硬组织部分中，根据其蛋白质成分的氨基酸组成表明存在两类不同的大分子。这两类大分子也存在于有孔虫的壳和各种软体动物中，它们都是通过“有机基质介导”的生物矿化过程形成的。这些大分子在牙齿和骨骼板中的位置尚不清楚，它们是否形成连贯结构也不清楚。因此，尽管所呈现的结果与这种解释一致，但现在就得出这些大分子确实起到有机基质的作用的结论还为时过早。
