Guegan Y, Pecker J
Neurochirurgie. 1979;25(4):232-8.
An experimental study about 36 nervous grafts on laboratory rats is reported. This study emphasizes the interest of microsurgical technique and, further more, the role of the number of stitches improving the results of each anastomosis and, thus, the quality of neural regeneration. In each animal, after sectioning tibial nerve, a graft (sciatic nerve same side) is interposed and sutured in three different ways; in a first lot of animals 6 stitches at the level of each anastomosis; in a 2nd lot: 2 stitches and in a 3d one a single stitch. The animals are tested at the end of the 20th week, with an electrophysiological control before being sacrified. The pathological controls take in account the number of regenerated nervous fibers below the graft. Our study confirm the superiority of results in the 6 stitches lot. The authors emphasize the role played by a watertight suture to prevent an anarchic growth of regenerating axones outside the graft.
本文报道了一项关于对实验大鼠进行36次神经移植的实验研究。该研究强调了显微外科技术的重要性，此外，还强调了缝合针数在改善每次吻合效果从而提高神经再生质量方面的作用。在每只动物身上，切断胫神经后，植入一段移植神经（同侧坐骨神经），并以三种不同方式进行缝合；在第一组动物中，每个吻合口缝6针；在第二组中缝2针；在第三组中只缝1针。在第20周结束时对动物进行测试，在处死动物前进行电生理检查。病理检查考虑移植神经下方再生神经纤维的数量。我们的研究证实了缝6针组效果更佳。作者强调了严密缝合在防止再生轴突在移植神经外无规则生长方面所起的作用。
