Youssef Sabrine Ben, Dghaies Rim, Toumi Afef, Njima Manel, Salem Randa, Fredj Myriam Ben, Ammar Nouha, Chabchoub Imene, Ksia Amine, Sahnoun Lassaad
Pediatric Surgery Department, Fattouma Bourguiba University Hospital, Street of June 1, 1995 - Monastir - 5000, Tunisia.
Anatomopathology Department, Fattouma Bourguiba University Hospital, Street of June 1, 1995 - Monastir - 5000, Tunisia.
J Surg Case Rep. 2025 Jan 31;2025(1):rjaf003. doi: 10.1093/jscr/rjaf003. eCollection 2025 Jan.
The simultaneous occurrence of Wilms tumor (WT) and multicystic kidney disease (MCKD) is extremely uncommon. Diagnosing WT in pediatric patients with multicystic dysplastic kidney (MCDK) substantially impacts management strategies, especially in surgical interventions and long-term outcomes. In summary, while the exact prevalence of WT in children with MCKD is not well-defined, children with MCDK are followed up throughout childhood by ultrasound because of the perceived risk of developing WT, although this risk is poorly defined and somewhat controversial. Herein, we present the case of an 8-year-old child diagnosed with WT arising in a clearly defined MCDK, discovered incidentally through histological analysis. This case contributes to the ongoing discussion by adding to the existing reports in the literature.
肾母细胞瘤（WT）与多囊肾病（MCKD）同时发生极为罕见。在患有多囊性发育不良肾（MCDK）的儿科患者中诊断出WT会对管理策略产生重大影响，尤其是在手术干预和长期预后方面。总之，虽然MCKD患儿中WT的确切患病率尚不明确，但由于存在发生WT的潜在风险，MCDK患儿在整个儿童期都要接受超声随访，尽管这种风险定义不明确且存在一定争议。在此，我们报告一例8岁儿童的病例，该患儿在明确诊断的MCDK中发生WT，通过组织学分析偶然发现。该病例通过补充文献中的现有报告，为正在进行的讨论做出了贡献。
