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聚碳酸酯/氧化铋纳米复合材料在γ射线领域实时应用的剂量学特性

Dosimetry characteristics of polycarbonate/bismuth oxide nanocomposite for real-time application in the field of gamma-rays.

作者信息

Veiskarami Amir, Malekie Shahryar, Kashian Sedigheh, Tajudin Suffian Mohamad

机构信息

Department of Medical Radiation Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran.

Radiation Application Research School, Nuclear Science and Technology Research Institute, Karaj, Iran.

出版信息

Rep Pract Oncol Radiother. 2024 Oct 3;29(4):413-425. doi: 10.5603/rpor.101397. eCollection 2024.

Abstract

BACKGROUND

Polymer-carbon nanostructures have previously been introduced for dosimetry of gamma rays with potential application in radiotherapy. In this research work, bismuth oxide (BiO) nanoparticles were added into the amorphous polycarbonate (PC) matrix to enhance the probability of the photoelectric effect and dosimetry response in parallel.

MATERIALS AND METHODS

PC/BiO nanocomposites at concentrations of 0, 5, 20, 40, and 50 BiO wt% were fabricated via a solution method. Afterward, the samples were irradiated by gamma rays of cobalt-60 (Co) related to Picker V-9, and Therarton-780 machines at 30-254 mGy/min. Dosimetric characteristics were carried out including linearity, angular dependency, energy, bias-polarity, field size, and repeatability.

RESULTS

Field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM) analyses exhibited an appropriate dispersion state. The dosimeter response was linear at 30-254 mGy/min for the all samples. The 50 wt% sample exhibited the highest sensitivity at 4.61 nC/mGy. A maximum angular variation of approximately 15% was recorded in normal beam incidence. The energy dependence at two energies of 662 and 1250 keV was obtained as 0.7%. Bias-polarity for the 40, and 50 wt% samples at 400 V were measured as 15.9% and 9.0%, respectively. The dosimetry response was significantly dependent on the radiation field size. Also, the repeatability of the dosimeter response was measured as 0.4%.

CONCLUSIONS

Considering the dosimetry characteristics of PC-BiO nanocomposites, and appropriate correction factors, this material can be used as a real-time dosimeter for the photon fields at therapy level.

摘要

背景

聚合物-碳纳米结构先前已被引入用于伽马射线剂量测定,在放射治疗中有潜在应用。在本研究工作中,将氧化铋(BiO)纳米颗粒添加到非晶聚碳酸酯(PC)基质中,以增强光电效应的概率并同时提高剂量测定响应。

材料与方法

通过溶液法制备了浓度为0、5、20、40和50 wt%的BiO的PC/BiO纳米复合材料。之后,样品用与Picker V-9和Therarton-780机器相关的钴-60(Co)伽马射线以30 - 254 mGy/分钟的剂量进行辐照。进行了剂量测定特性研究,包括线性、角度依赖性、能量、偏置极性、射野大小和重复性。

结果

场发射扫描电子显微镜(FESEM)和透射电子显微镜(TEM)分析显示出合适的分散状态。所有样品在30 - 254 mGy/分钟时剂量计响应呈线性。50 wt%的样品在4.61 nC/mGy时表现出最高灵敏度。在正常束入射时记录到最大角度变化约为15%。在662和1250 keV两种能量下的能量依赖性为0.7%。400 V时40 wt%和50 wt%样品的偏置极性分别测量为15.9%和9.0%。剂量测定响应显著依赖于辐射野大小。此外,剂量计响应的重复性测量为0.4%。

结论

考虑到PC - BiO纳米复合材料的剂量测定特性以及合适的校正因子,这种材料可作为治疗水平光子场的实时剂量计。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfff/11785392/97925356b143/rpor-29-4-413f1.jpg

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