Witham Miles D, Bartle Victoria, Bellass Sue, Bunn Jonathan G, Cartner Duncan, Cordell Heather J, Doal Rominique, Evison Felicity, Gallier Suzy, Harris Steve, Hillman Susan J, Holding Ray, Leroux Peta, Marshall Tom, Matthews Fiona E, Missier Paolo, Nair Anand, Osman Mo, Pearson Ewan R, Plummer Chris, Pretorius Sara, Richardson Sarah J, Robinson Sian M, Sapey Elizabeth, Scharf Thomas, Shah Rupal, Shahmandi Marzieh, Singer Mervyn, Suklan Jana, Wason James Ms, Cooper Rachel, Sayer Avan A
AGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK.
NIHR Newcastle Biomedical Research Centre, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust and Newcastle University, Newcastle Upon Tyne, UK.
J Multimorb Comorb. 2025 Feb 1;15:26335565251317940. doi: 10.1177/26335565251317940. eCollection 2025 Jan-Dec.
Multiple long-term conditions (MLTCs; commonly referred to as multimorbidity) are highly prevalent among people admitted to hospital and are therefore of critical importance to hospital-based healthcare systems. To date, most research on MLTCs has been conducted in primary care or the general population with comparatively little work undertaken in the hospital setting.
To describe the rationale and content of ADMISSION: a four-year UK Research and Innovation and National Institute of Health and Care Research funded interdisciplinary programme that seeks, in partnership with public contributors, to transform care for people living with MLTCs admitted to hospital.
Based across five UK academic centres, ADMISSION combines expertise in clinical medicine, epidemiology, informatics, computing, biostatistics, social science, genetics and care pathway mapping to examine patterns of conditions, mechanisms, consequences and pathways of care for people with MLTCs admitted to hospital.
The programme uses routinely collected electronic health record data from large UK teaching hospitals, population-based cohort data from UK Biobank and routinely collected blood samples from The Scottish Health Research Register and Biobank (SHARE). These approaches are complemented by focused qualitative work exploring the perspectives of healthcare professionals and the lived experience of people with MLTCs admitted to hospital.
ADMISSION will provide the necessary foundations to develop novel ways to prevent and treat MLTCs and their consequences in people admitted to hospital and to improve care systems and the quality of care for this underserved group.
多种长期病症(MLTCs;通常称为共病)在住院患者中极为普遍,因此对医院医疗系统至关重要。迄今为止,大多数关于MLTCs的研究是在初级保健或普通人群中进行的,在医院环境中开展的工作相对较少。
描述“入院”(ADMISSION)的基本原理和内容:这是一个由英国研究与创新署和国家卫生与保健研究机构资助的为期四年的跨学科项目,该项目与公众参与者合作,旨在改变对住院的MLTCs患者的护理方式。
“入院”项目以英国五个学术中心为基础,整合了临床医学、流行病学、信息学、计算机科学、生物统计学、社会科学、遗传学和护理路径映射等方面的专业知识,以研究住院的MLTCs患者的病症模式、机制、后果及护理路径。
该项目使用从英国大型教学医院常规收集的电子健康记录数据、来自英国生物银行的基于人群的队列数据,以及从苏格兰健康研究登记处和生物银行(SHARE)常规收集的血样。这些方法辅以有针对性的定性研究,以探索医疗保健专业人员的观点以及住院的MLTCs患者的实际经历。
“入院”项目将为开发预防和治疗MLTCs及其对住院患者造成的后果的新方法提供必要基础,并改善针对这一服务不足群体的护理系统和护理质量。