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吸入大麻导致的弥漫性肺泡出血

Diffuse Alveolar Hemorrhage Due to Cannabis Inhalation.

作者信息

Jaquez Duran Maria, Venkatram Sindhaghatta, Diaz-Fuentes Gilda

机构信息

Pulmonary and Critical Care, BronxCare Health System, Bronx, USA.

出版信息

Cureus. 2025 Jan 1;17(1):e76755. doi: 10.7759/cureus.76755. eCollection 2025 Jan.

Abstract

We report the case of a 34-year-old female who presented with acute respiratory failure and hemoptysis, requiring intubation and mechanical ventilation. Fiberoptic bronchoscopy revealed progressively bloodier returns during lavage, consistent with diffuse alveolar hemorrhage (DAH). This case highlights DAH as a rare but severe complication associated with cannabis use. DAH involves bleeding into the alveolar spaces, impairing gas exchange and causing respiratory distress. While cannabis use is not a well-established cause, this case underscores its potential to trigger serious respiratory complications. Recurrent DAH episodes can lead to long-term complications, such as interstitial fibrosis and emphysema, resulting in obstructive spirometry patterns. Acute complications, including shock, renal failure, and barotrauma, further highlight the critical need for early intervention. Raising awareness among healthcare providers about the potential link between cannabis use and DAH is essential for prompt recognition and management, ultimately improving patient outcomes. This case adds to the limited literature on cannabis-induced DAH, emphasizing its clinical significance.

摘要

我们报告了一例34岁女性病例,该患者出现急性呼吸衰竭和咯血,需要进行插管和机械通气。纤维支气管镜检查显示灌洗过程中回抽液的血性逐渐增加,符合弥漫性肺泡出血(DAH)。该病例突出了DAH作为与大麻使用相关的一种罕见但严重的并发症。DAH涉及血液进入肺泡腔,损害气体交换并导致呼吸窘迫。虽然大麻使用并非公认的病因,但该病例强调了其引发严重呼吸并发症的可能性。复发性DAH发作可导致长期并发症,如间质性纤维化和肺气肿,导致肺功能检查出现阻塞性模式。急性并发症,包括休克、肾衰竭和气压伤,进一步凸显了早期干预的迫切需求。提高医疗保健提供者对大麻使用与DAH之间潜在联系的认识,对于及时识别和管理至关重要,最终可改善患者预后。该病例补充了关于大麻所致DAH的有限文献,强调了其临床意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22e4/11785422/880d41111743/cureus-0017-00000076755-i01.jpg

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